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Increased sphingosine-1-phosphate improves muscle regeneration in acutely injured mdx mice

Overview of attention for article published in Skeletal Muscle, August 2013
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#6 of 360)
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

news
5 news outlets
blogs
1 blog
patent
1 patent
facebook
1 Facebook page

Citations

dimensions_citation
50 Dimensions

Readers on

mendeley
45 Mendeley
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Title
Increased sphingosine-1-phosphate improves muscle regeneration in acutely injured mdx mice
Published in
Skeletal Muscle, August 2013
DOI 10.1186/2044-5040-3-20
Pubmed ID
Authors

Nicholas Ieronimakis, Mario Pantoja, Aislinn L Hays, Timothy L Dosey, Junlin Qi, Karin A Fischer, Andrew N Hoofnagle, Martin Sadilek, Jeffrey S Chamberlain, Hannele Ruohola-Baker, Morayma Reyes

Abstract

Presently, there is no effective treatment for the lethal muscle wasting disease Duchenne muscular dystrophy (DMD). Here we show that increased sphingosine-1-phoshate (S1P) through direct injection or via the administration of the small molecule 2-acetyl-4(5)-tetrahydroxybutyl imidazole (THI), an S1P lyase inhibitor, has beneficial effects in acutely injured dystrophic muscles of mdx mice.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 45 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 22%
Student > Ph. D. Student 7 16%
Student > Bachelor 5 11%
Student > Master 5 11%
Professor > Associate Professor 3 7%
Other 5 11%
Unknown 10 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 31%
Biochemistry, Genetics and Molecular Biology 6 13%
Medicine and Dentistry 4 9%
Chemistry 3 7%
Sports and Recreations 2 4%
Other 4 9%
Unknown 12 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 46. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 April 2021.
All research outputs
#764,511
of 22,715,151 outputs
Outputs from Skeletal Muscle
#6
of 360 outputs
Outputs of similar age
#6,902
of 198,390 outputs
Outputs of similar age from Skeletal Muscle
#1
of 5 outputs
Altmetric has tracked 22,715,151 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 360 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 198,390 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them