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Biomedical Nanotechnology

Overview of attention for book
Cover of 'Biomedical Nanotechnology'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 Quantification of siRNA Duplexes Bound to Gold Nanoparticle Surfaces
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    Chapter 2 Ligand Exchange and 1H NMR Quantification of Single- and Mixed-Moiety Thiolated Ligand Shells on Gold Nanoparticles
  4. Altmetric Badge
    Chapter 3 Nanoparticle Tracking Analysis for Determination of Hydrodynamic Diameter, Concentration, and Zeta-Potential of Polyplex Nanoparticles
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    Chapter 4 Magnetic Characterization of Iron Oxide Nanoparticles for Biomedical Applications
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    Chapter 5 Preparation of Magnetic Nanoparticles for Biomedical Applications
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    Chapter 6 Brain-Penetrating Nanoparticles for Analysis of the Brain Microenvironment
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    Chapter 7 Volumetric Bar-Chart Chips for Biosensing
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    Chapter 8 qFlow Cytometry-Based Receptoromic Screening: A High-Throughput Quantification Approach Informing Biomarker Selection and Nanosensor Development
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    Chapter 9 Evaluating Nanoparticle Binding to Blood Compartment Immune Cells in High-Throughput with Flow Cytometry
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    Chapter 10 A Gold@Polydopamine Core–Shell Nanoprobe for Long-Term Intracellular Detection of MicroRNAs in Differentiating Stem Cells
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    Chapter 11 Antibody-Conjugated Single Quantum Dot Tracking of Membrane Neurotransmitter Transporters in Primary Neuronal Cultures
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    Chapter 12 Spectroscopic Photoacoustic Imaging of Gold Nanorods
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    Chapter 13 Dual Wavelength-Triggered Gold Nanorods for Anticancer Treatment
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    Chapter 14 Photolabile Self-Immolative DNA-Drug Nanostructures
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    Chapter 15 Enzyme-Responsive Nanoparticles for the Treatment of Disease
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    Chapter 16 NanoScript: A Versatile Nanoparticle-Based Synthetic Transcription Factor for Innovative Gene Manipulation
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    Chapter 17 Glucose-Responsive Insulin Delivery by Microneedle-Array Patches Loaded with Hypoxia-Sensitive Vesicles
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    Chapter 18 Electrospun Nanofiber Scaffolds and Their Hydrogel Composites for the Engineering and Regeneration of Soft Tissues
  20. Altmetric Badge
    Chapter 19 Application of Hydrogel Template Strategy in Ocular Drug Delivery
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    Chapter 20 High-Accuracy Determination of Cytotoxic Responses from Graphene Oxide Exposure Using Imaging Flow Cytometry
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    Chapter 21 Air–Liquid Interface Cell Exposures to Nanoparticle Aerosols
  23. Altmetric Badge
    Chapter 22 Returning to the Patent Landscapes for Nanotechnology: Assessing the Garden that It Has Grown Into
  24. Altmetric Badge
    Chapter 23 Erratum to: Biomedical Nanotechnology
Attention for Chapter 3: Nanoparticle Tracking Analysis for Determination of Hydrodynamic Diameter, Concentration, and Zeta-Potential of Polyplex Nanoparticles
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

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1 news outlet

Citations

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13 Dimensions

Readers on

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36 Mendeley
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Chapter title
Nanoparticle Tracking Analysis for Determination of Hydrodynamic Diameter, Concentration, and Zeta-Potential of Polyplex Nanoparticles
Chapter number 3
Book title
Biomedical Nanotechnology
Published in
Methods in molecular biology, February 2017
DOI 10.1007/978-1-4939-6840-4_3
Pubmed ID
Book ISBNs
978-1-4939-6838-1, 978-1-4939-6840-4
Authors

David R. Wilson, Jordan J. Green, Wilson, David R., Green, Jordan J.

Editors

Sarah Hurst Petrosko, Emily S. Day

Abstract

Nanoparticle tracking analysis (NTA) is a recently developed nanoparticle characterization technique that offers certain advantages over dynamic light scattering for characterizing polyplex nanoparticles in particular. Dynamic light scattering results in intensity-weighted average measurements of nanoparticle characteristics. In contrast, NTA directly tracks individual particles, enabling concentration measurements as well as the direct determination of number-weighted particle size and zeta-potential. A direct number-weighted assessment of nanoparticle characteristics is particularly useful for polydisperse samples of particles, including many varieties of gene delivery particles that can be prone to aggregation. Here, we describe the synthesis of poly(beta-amino ester)/deoxyribonucleic acid (PBAE/DNA) polyplex nanoparticles and their characterization using NTA to determine hydrodynamic diameter, zeta-potential, and concentration. Additionally, we detail methods of labeling nucleic acids with fluorophores to assess only those polyplex nanoparticles containing plasmids via NTA. Polymeric gene delivery of exogenous plasmid DNA has great potential for treating a wide variety of diseases by inducing cells to express a gene of interest.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Unknown 35 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 22%
Student > Bachelor 6 17%
Student > Master 5 14%
Researcher 4 11%
Student > Doctoral Student 2 6%
Other 3 8%
Unknown 8 22%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 7 19%
Pharmacology, Toxicology and Pharmaceutical Science 6 17%
Chemical Engineering 5 14%
Chemistry 3 8%
Physics and Astronomy 2 6%
Other 5 14%
Unknown 8 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 October 2022.
All research outputs
#3,938,378
of 23,543,207 outputs
Outputs from Methods in molecular biology
#1,008
of 13,395 outputs
Outputs of similar age
#70,131
of 313,621 outputs
Outputs of similar age from Methods in molecular biology
#13
of 264 outputs
Altmetric has tracked 23,543,207 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,395 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,621 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 264 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.