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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Single-cell transcriptome conservation in cryopreserved cells and tissues
|
|---|---|
| Published in |
Genome Biology, March 2017
|
| DOI | 10.1186/s13059-017-1171-9 |
| Pubmed ID | |
| Authors |
Amy Guillaumet-Adkins, Gustavo Rodríguez-Esteban, Elisabetta Mereu, Maria Mendez-Lago, Diego A. Jaitin, Alberto Villanueva, August Vidal, Alex Martinez-Marti, Enriqueta Felip, Ana Vivancos, Hadas Keren-Shaul, Simon Heath, Marta Gut, Ido Amit, Ivo Gut, Holger Heyn |
| Abstract |
A variety of single-cell RNA preparation procedures have been described. So far, protocols require fresh material, which hinders complex study designs. We describe a sample preservation method that maintains transcripts in viable single cells, allowing one to disconnect time and place of sampling from subsequent processing steps. We sequence single-cell transcriptomes from >1000 fresh and cryopreserved cells using 3'-end and full-length RNA preparation methods. Our results confirm that the conservation process did not alter transcriptional profiles. This substantially broadens the scope of applications in single-cell transcriptomics and could lead to a paradigm shift in future study designs. |
X Demographics
The data shown below were collected from the profiles of 59 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 13 | 22% |
| Spain | 7 | 12% |
| United Kingdom | 5 | 8% |
| Israel | 2 | 3% |
| Australia | 2 | 3% |
| Germany | 1 | 2% |
| Japan | 1 | 2% |
| Hong Kong | 1 | 2% |
| Belgium | 1 | 2% |
| Other | 4 | 7% |
| Unknown | 22 | 37% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 30 | 51% |
| Members of the public | 27 | 46% |
| Practitioners (doctors, other healthcare professionals) | 1 | 2% |
| Science communicators (journalists, bloggers, editors) | 1 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 495 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | <1% |
| Austria | 1 | <1% |
| Sweden | 1 | <1% |
| United Kingdom | 1 | <1% |
| Denmark | 1 | <1% |
| Japan | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 488 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 129 | 26% |
| Student > Ph. D. Student | 108 | 22% |
| Student > Bachelor | 35 | 7% |
| Student > Master | 24 | 5% |
| Student > Doctoral Student | 24 | 5% |
| Other | 81 | 16% |
| Unknown | 94 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 128 | 26% |
| Agricultural and Biological Sciences | 102 | 21% |
| Medicine and Dentistry | 66 | 13% |
| Immunology and Microbiology | 29 | 6% |
| Neuroscience | 16 | 3% |
| Other | 44 | 9% |
| Unknown | 110 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 59. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 January 2020.
All research outputs
#720,053
of 25,382,440 outputs
Outputs from Genome Biology
#465
of 4,468 outputs
Outputs of similar age
#15,040
of 324,443 outputs
Outputs of similar age from Genome Biology
#14
of 67 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,468 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,443 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.