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Longitudinal transcriptomic dysregulation in the peripheral blood of transgenic Huntington’s disease monkeys

Overview of attention for article published in BMC Neuroscience, August 2013
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Title
Longitudinal transcriptomic dysregulation in the peripheral blood of transgenic Huntington’s disease monkeys
Published in
BMC Neuroscience, August 2013
DOI 10.1186/1471-2202-14-88
Pubmed ID
Authors

Jannet Kocerha, Yuhong Liu, David Willoughby, Kumaravel Chidamparam, Joseph Benito, Kate Nelson, Yan Xu, Tim Chi, Heidi Engelhardt, Sean Moran, Shang-Hsun Yang, Shi-Hua Li, Xiao-Jiang Li, Katherine Larkin, Adam Neumann, Heather Banta, Jin Jing Yang, Anthony WS Chan

Abstract

Huntington's Disease (HD) is a progressive neurodegenerative disorder caused by an expansion in the polyglutamine (polyQ) region of the Huntingtin (HTT) gene. The clinical features of HD are characterized by cognitive, psychological, and motor deficits. Molecular instability, a core component in neurological disease progression, can be comprehensively evaluated through longitudinal transcriptomic profiling. Development of animal models amenable to longitudinal examination enables distinct disease-associated mechanisms to be identified.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 6%
India 1 3%
Portugal 1 3%
Unknown 31 89%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 31%
Researcher 5 14%
Student > Bachelor 4 11%
Student > Postgraduate 3 9%
Professor > Associate Professor 2 6%
Other 2 6%
Unknown 8 23%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 26%
Medicine and Dentistry 5 14%
Biochemistry, Genetics and Molecular Biology 4 11%
Neuroscience 4 11%
Psychology 2 6%
Other 2 6%
Unknown 9 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 August 2013.
All research outputs
#20,198,525
of 22,716,996 outputs
Outputs from BMC Neuroscience
#1,052
of 1,241 outputs
Outputs of similar age
#174,356
of 198,616 outputs
Outputs of similar age from BMC Neuroscience
#47
of 60 outputs
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So far Altmetric has tracked 1,241 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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