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Leprosy and hepatitis B coinfection in southern Brazil

Overview of attention for article published in Brazilian Journal of Infectious Diseases, August 2013
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Title
Leprosy and hepatitis B coinfection in southern Brazil
Published in
Brazilian Journal of Infectious Diseases, August 2013
DOI 10.1016/j.bjid.2013.04.003
Pubmed ID
Authors

Cleverson Leitão, Denis Ueda, Anna Carolina de Moraes Braga, Angelica B.W. Boldt, Iara J.T. Messias-Reason

Abstract

To investigate the association of leprosy with hepatitis B virus (HBV) infection, as yet unknown for South Brazil, we assessed hepatitis B virus coinfection in 199 South Brazilian leprosy patients (119 lepromatous, 15 tuberculoid, 30 borderline, 12 undetermined and 23 unspecified) and in 681 matched blood donors by screening for the hepatitis B virus markers HBSAg and anti-HBc, using ELISA. Positive samples were retested and anti-HBc+ only samples were tested for the hepatitis B surface antibody (anti-HBs). There was a strong association between leprosy and hepatitis B virus infection (OR=9.8, 95% CI=6.4-14.7; p=0.004 · E(-30)), as well as an association between HBV infection and lepromatous leprosy, compared to other forms (OR=2.4, 95% CI=1.2-4.8; p=0.017). We also found that confinement due to leprosy was associated with hepatitis B virus infection (OR=3.9, 95% CI=2.1-7.4; p=0.015 · E(-3)). Leprosy patients are susceptible to develop hepatitis B virus infection, especially lepromatous. Institutionalized patients, who probably present a stronger Th2 response, have higher risk of being exposed to hepatitis B virus. This clearly emphasizes the need for special care to leprosy patients in preventing hepatitis B virus coinfection in South Brazil.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 4%
Unknown 46 96%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 7 15%
Student > Master 7 15%
Student > Bachelor 7 15%
Student > Doctoral Student 5 10%
Student > Ph. D. Student 5 10%
Other 11 23%
Unknown 6 13%
Readers by discipline Count As %
Medicine and Dentistry 17 35%
Nursing and Health Professions 7 15%
Agricultural and Biological Sciences 6 13%
Biochemistry, Genetics and Molecular Biology 4 8%
Arts and Humanities 2 4%
Other 4 8%
Unknown 8 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 September 2013.
All research outputs
#23,065,269
of 25,707,225 outputs
Outputs from Brazilian Journal of Infectious Diseases
#645
of 811 outputs
Outputs of similar age
#187,033
of 209,685 outputs
Outputs of similar age from Brazilian Journal of Infectious Diseases
#13
of 16 outputs
Altmetric has tracked 25,707,225 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 811 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 209,685 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.