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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Genome architecture is a selectable trait that can be maintained by antagonistic pleiotropy
|
|---|---|
| Published in |
Nature Communications, August 2013
|
| DOI | 10.1038/ncomms3235 |
| Pubmed ID | |
| Authors |
Ana Teresa Avelar, Lília Perfeito, Isabel Gordo, Miguel Godinho Ferreira |
| Abstract |
Chromosomal rearrangements are mutations contributing to both within and between species variation; however their contribution to fitness is yet to be measured. Here we show that chromosomal rearrangements are pervasive in natural isolates of Schizosaccharomyces pombe and contribute to reproductive isolation. To determine the fitness effects of chromosome structure, we constructed two inversions and eight translocations without changing the coding sequence. We show that chromosomal rearrangements contribute to both reproductive success in meiosis and growth rate in mitosis with a strong genotype by environment interaction. These changes are accompanied by alterations in gene expression. Strikingly, we find several examples leading to antagonistic pleiotropy. Even though chromosomal rearrangements may have a deleterious effect during sexual reproduction, some compensate with a strong growth advantage in mitosis. Our results constitute the first quantification of fitness effects caused by de novo mutations that result in chromosomal rearrangement variation and suggest a mechanism for their maintenance in natural populations. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 25% |
| France | 1 | 25% |
| United States | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 3 | 75% |
| Members of the public | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 125 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 3 | 2% |
| United States | 3 | 2% |
| Portugal | 2 | 2% |
| United Kingdom | 2 | 2% |
| Sweden | 1 | <1% |
| Belgium | 1 | <1% |
| Germany | 1 | <1% |
| Unknown | 112 | 90% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 30 | 24% |
| Student > Ph. D. Student | 29 | 23% |
| Student > Master | 15 | 12% |
| Student > Bachelor | 14 | 11% |
| Professor > Associate Professor | 7 | 6% |
| Other | 19 | 15% |
| Unknown | 11 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 76 | 61% |
| Biochemistry, Genetics and Molecular Biology | 31 | 25% |
| Medicine and Dentistry | 2 | 2% |
| Mathematics | 1 | <1% |
| Physics and Astronomy | 1 | <1% |
| Other | 3 | 2% |
| Unknown | 11 | 9% |
Attention Score in Context
This research output has an Altmetric Attention Score of 36. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 February 2020.
All research outputs
#937,056
of 22,716,996 outputs
Outputs from Nature Communications
#14,998
of 46,757 outputs
Outputs of similar age
#8,747
of 199,028 outputs
Outputs of similar age from Nature Communications
#105
of 365 outputs
Altmetric has tracked 22,716,996 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 46,757 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 55.5. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 199,028 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 365 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.