Title |
Resistance training to improve type 2 diabetes: working toward a prescription for the future
|
---|---|
Published in |
Nutrition & Metabolism, March 2017
|
DOI | 10.1186/s12986-017-0173-7 |
Pubmed ID | |
Authors |
Dominik H. Pesta, Renata L. S. Goncalves, Anila K. Madiraju, Barbara Strasser, Lauren M. Sparks |
Abstract |
The prevalence of type 2 diabetes (T2D) is rapidly increasing, and effective strategies to manage and prevent this disease are urgently needed. Resistance training (RT) promotes health benefits through increased skeletal muscle mass and qualitative adaptations, such as enhanced glucose transport and mitochondrial oxidative capacity. In particular, mitochondrial adaptations triggered by RT provide evidence for this type of exercise as a feasible lifestyle recommendation to combat T2D, a disease typically characterized by altered muscle mitochondrial function. Recently, the synergistic and antagonistic effects of combined training and Metformin use have come into question and warrant more in-depth prospective investigations. In the future, clinical intervention studies should elucidate the mechanisms driving RT-mitigated mitochondrial adaptations in muscle and their link to improvements in glycemic control, cholesterol metabolism and other cardiovascular disease risk factors in individuals with T2D. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 14 | 14% |
Spain | 7 | 7% |
France | 4 | 4% |
United Kingdom | 4 | 4% |
Canada | 3 | 3% |
Chile | 3 | 3% |
Australia | 2 | 2% |
Sweden | 2 | 2% |
Netherlands | 2 | 2% |
Other | 13 | 13% |
Unknown | 43 | 44% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 67 | 69% |
Practitioners (doctors, other healthcare professionals) | 18 | 19% |
Scientists | 12 | 12% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 284 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 48 | 17% |
Student > Master | 41 | 14% |
Student > Ph. D. Student | 28 | 10% |
Researcher | 21 | 7% |
Student > Postgraduate | 16 | 6% |
Other | 50 | 17% |
Unknown | 82 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Sports and Recreations | 59 | 21% |
Medicine and Dentistry | 41 | 14% |
Nursing and Health Professions | 40 | 14% |
Biochemistry, Genetics and Molecular Biology | 18 | 6% |
Agricultural and Biological Sciences | 12 | 4% |
Other | 30 | 10% |
Unknown | 86 | 30% |