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Attention Score in Context
| Title |
Blood cholesterol in late-life and cognitive decline: a longitudinal study of the Chinese elderly
|
|---|---|
| Published in |
Molecular Neurodegeneration, March 2017
|
| DOI | 10.1186/s13024-017-0167-y |
| Pubmed ID | |
| Authors |
Chaoran Ma, Zhaoxue Yin, Pengfei Zhu, Jiesi Luo, Xiaoming Shi, Xiang Gao |
| Abstract |
Previous studies regarding the lipid-cognition relation in older adults are limited and have generated mixed results. We thus examined whether higher blood cholesterol concentrations were associated with faster cognitive decline in a community-based longitudinal study of Chinese elderly. The study included 1,159 Chinese adults aged over 60 years (women: 48.7%, mean age: 79.4 years), who were free of dementia, Parkinson disease and stroke at the baseline. Blood concentrations of total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG), were assessed at the baseline. Global cognitive functions were assessed using the Chinese Mini-Mental State Examination (MMSE) at in 2009, 2012 and 2014. Association between blood cholesterol and repeated cognitive function was analyzed with linear mixed models, adjusting for sociodemographic information, behavior and lifestyle, depression symptoms, physical examination, hypertension, and laboratory indexes. Higher baseline TC and LDL-C concentrations were significantly associated with greater cognitive decline. Adjusted mean difference in cognitive decline rate, comparing two extreme quartiles, was 0.28 points (MMSE score) per year (95% confident interval (CI): -0.54,-0.02; P-trend = 0.005) for TC and 0.42 points per year (95% CI: -0.69, -0.16; P-trend = 0.006) for LDL-C. In a subgroup analysis, the associations between all lipids and cognitive decline appeared to be more pronounced among individuals aged 100 years or older (n = 90), relative to others. Higher blood concentrations of TC and LDL-C in late-life were associated with faster global cognitive decline. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 164 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 164 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 24 | 15% |
| Student > Master | 17 | 10% |
| Student > Bachelor | 17 | 10% |
| Researcher | 13 | 8% |
| Student > Postgraduate | 10 | 6% |
| Other | 25 | 15% |
| Unknown | 58 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 25 | 15% |
| Psychology | 15 | 9% |
| Nursing and Health Professions | 10 | 6% |
| Neuroscience | 10 | 6% |
| Biochemistry, Genetics and Molecular Biology | 6 | 4% |
| Other | 31 | 19% |
| Unknown | 67 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 March 2017.
All research outputs
#18,536,772
of 22,958,253 outputs
Outputs from Molecular Neurodegeneration
#790
of 852 outputs
Outputs of similar age
#235,117
of 307,995 outputs
Outputs of similar age from Molecular Neurodegeneration
#18
of 20 outputs
Altmetric has tracked 22,958,253 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 852 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.