↓ Skip to main content

The nature of human sperm head vacuoles: a systematic literature review

Overview of attention for article published in Basic and Clinical Andrology, August 2013
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)

Mentioned by

1 blog
1 tweeter
1 Wikipedia page


14 Dimensions

Readers on

24 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
The nature of human sperm head vacuoles: a systematic literature review
Published in
Basic and Clinical Andrology, August 2013
DOI 10.1186/2051-4190-23-3
Pubmed ID

Florence Boitrelle, Bruno Guthauser, Laura Alter, Marc Bailly, Robert Wainer, François Vialard, Martine Albert, Jacqueline Selva


Motile sperm organelle morphology examination (MSOME) involves the use of differential interference contrast microscopy (also called Nomarski contrast) at high magnification (at least 6300x) to improve the observation of live human spermatozoa. In fact, this technique evidences sperm head vacuoles that are not necessarily seen at lower magnifications - particularly if the vacuoles are small (i.e. occupying <4% of the sperm head's area). However, a decade after MSOME's introduction, it is still not clear whether sperm head vacuoles are nuclear, acrosomal and/or membrane-related in nature. In an attempt to clarify this debate, we performed a systematic literature review in accordance with the PRISMA guidelines. The PubMed database was searched from 2001 onwards with the terms "MSOME", "human sperm vacuoles", "high-magnification, sperm". Out of 180 search results, 21 relevant English-language publications on the nature of human sperm head vacuoles were finally selected and reviewed. Our review of the literature prompted us to conclude that sperm-head vacuoles are nuclear in nature and are related to chromatin condensation failure and (in some cases) sperm DNA damage.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Algeria 1 4%
Unknown 23 96%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 5 21%
Other 3 13%
Researcher 3 13%
Student > Ph. D. Student 3 13%
Student > Doctoral Student 2 8%
Other 8 33%
Readers by discipline Count As %
Medicine and Dentistry 9 38%
Biochemistry, Genetics and Molecular Biology 7 29%
Agricultural and Biological Sciences 3 13%
Nursing and Health Professions 1 4%
Earth and Planetary Sciences 1 4%
Other 2 8%
Unknown 1 4%

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 March 2018.
All research outputs
of 12,582,044 outputs
Outputs from Basic and Clinical Andrology
of 49 outputs
Outputs of similar age
of 155,907 outputs
Outputs of similar age from Basic and Clinical Andrology
of 3 outputs
Altmetric has tracked 12,582,044 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 49 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.9. This one scored the same or higher as 41 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 155,907 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them