Title |
There is no evident correlation between interleukin-10 gene polymorphisms and periportal fibrosis regression after specific treatment
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Published in |
Revista da Sociedade Brasileira de Medicina Tropical, December 2016
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DOI | 10.1590/0037-8682-0141-2016 |
Pubmed ID | |
Authors |
Paula Carolina Valença Silva, Aline Vieira da Silva, Taysa Nascimento Silva, Letícia Moura de Vasconcelos, Adriana Vieira Gomes, Maria Rosângela Cunha Duarte Coêlho, Maria Tereza Cartaxo Muniz, Ana Lúcia Coutinho Domingues |
Abstract |
We evaluated the associations between interleukin-10 (IL-10) gene polymorphisms -G1082A/-C819T/-C592A and periportal fibrosis regression after specific treatment for schistosomiasis. This retrospective cohort study involved 125 Brazilian patients infected with Schistosomiasis mansoni, who were followed up for 2 years after specific treatment to estimate the probability of periportal fibrosis regression. There was no evidence of associations between IL-10 polymorphisms and periportal fibrosis regression after treatment. There was no evidence of associations between gene promoter polymorphisms of IL-10 and the regression of periportal fibrosis in this Brazilian population. |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 17 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 5 | 29% |
Librarian | 2 | 12% |
Researcher | 2 | 12% |
Student > Bachelor | 1 | 6% |
Lecturer | 1 | 6% |
Other | 2 | 12% |
Unknown | 4 | 24% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 6 | 35% |
Agricultural and Biological Sciences | 2 | 12% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 6% |
Biochemistry, Genetics and Molecular Biology | 1 | 6% |
Immunology and Microbiology | 1 | 6% |
Other | 1 | 6% |
Unknown | 5 | 29% |