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Inflammatory bowel disease following anti-interleukin-1-treatment in systemic juvenile idiopathic arthritis

Overview of attention for article published in Pediatric Rheumatology, March 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (74th percentile)

Mentioned by

twitter
11 tweeters
facebook
1 Facebook page

Readers on

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44 Mendeley
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Title
Inflammatory bowel disease following anti-interleukin-1-treatment in systemic juvenile idiopathic arthritis
Published in
Pediatric Rheumatology, March 2017
DOI 10.1186/s12969-017-0147-3
Pubmed ID
Authors

Boris Hügle, Fabian Speth, Johannes-Peter Haas

Abstract

Inflammatory bowel disease can develop in the context of some rheumatic diseases in childhood, including juvenile idiopathic arthritis (JIA). Inflammatory bowel disease (IBD) is frequently associated with other immune-mediated diseases; however, systemic onset JIA (sJIA) has not previously been connected to IBD. Treatment of sJIA has significantly changed in recent years, possibly causing changes in inflammatory patterns. Therefore, data from the German Center for Pediatric and Adolescent Rheumtology from 2010 until 2015 were analyzed by retrospective chart review. Eighty-two patients with confirmed diagosis of sJIA were found. Of these, three were identified with a diagnosis of IBD confirmed by colonoscopy (two cases of Crohn's disease, one case of ulcerative colitis) 0.8 - 4.3 years after diagnosis. All three were treated with IL-1 antagonists (anakinra in two cases, canakinumab in one case) and were well controlled for sJIA symptoms at time of diagnosis of IBD CONCLUSIONS: IBD seems to be a rare, but possible complication of sJIA. Treatment with IL-1 antagonists might be a relevant factor for a switch in the clinical phenotype of the underlying inflammatory process.

Twitter Demographics

The data shown below were collected from the profiles of 11 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 44 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 27%
Student > Master 8 18%
Student > Bachelor 4 9%
Professor 3 7%
Professor > Associate Professor 3 7%
Other 7 16%
Unknown 7 16%
Readers by discipline Count As %
Medicine and Dentistry 24 55%
Immunology and Microbiology 3 7%
Agricultural and Biological Sciences 3 7%
Nursing and Health Professions 2 5%
Biochemistry, Genetics and Molecular Biology 1 2%
Other 3 7%
Unknown 8 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2017.
All research outputs
#2,591,631
of 14,465,106 outputs
Outputs from Pediatric Rheumatology
#104
of 428 outputs
Outputs of similar age
#66,408
of 259,283 outputs
Outputs of similar age from Pediatric Rheumatology
#1
of 1 outputs
Altmetric has tracked 14,465,106 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 428 research outputs from this source. They receive a mean Attention Score of 4.6. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 259,283 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them