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Tracking the genomic evolution of breast cancer metastasis

Overview of attention for article published in Breast Cancer Research, February 2010
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Title
Tracking the genomic evolution of breast cancer metastasis
Published in
Breast Cancer Research, February 2010
DOI 10.1186/bcr2469
Pubmed ID
Authors

Davide Zecchin, Alberto Bardelli

Abstract

Therapeutic choices for metastatic tumors are, in most cases, based upon the histological and molecular analysis of the corresponding primary tumor. Understanding whether and to what extent the genomic landscape of metastasis differs from the tumors from which they originated is critical yet largely unknown. A recent report tackled this key issue by comparing the genomic and transcriptional profile of a metastatic lobular breast tumor with that of the primary tumor surgically removed 9 years earlier. The extent of the differences suggests a high degree of mutational heterogeneity between primary and metastatic lesions and indicates that significant evolution occurs during breast cancer progression.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 1 2%
Unknown 46 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 19%
Professor > Associate Professor 3 6%
Student > Ph. D. Student 3 6%
Other 2 4%
Student > Bachelor 2 4%
Other 2 4%
Unknown 26 55%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 15%
Biochemistry, Genetics and Molecular Biology 6 13%
Medicine and Dentistry 6 13%
Physics and Astronomy 1 2%
Materials Science 1 2%
Other 0 0%
Unknown 26 55%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 September 2013.
All research outputs
#17,283,763
of 25,371,288 outputs
Outputs from Breast Cancer Research
#1,534
of 2,052 outputs
Outputs of similar age
#143,158
of 172,629 outputs
Outputs of similar age from Breast Cancer Research
#11
of 11 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,052 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 172,629 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.