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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Hereditary breast cancer: ever more pieces to the polygenic puzzle
|
|---|---|
| Published in |
Hereditary Cancer in Clinical Practice, September 2013
|
| DOI | 10.1186/1897-4287-11-12 |
| Pubmed ID | |
| Authors |
Natalia Bogdanova, Sonja Helbig, Thilo Dörk |
| Abstract |
Several susceptibility genes differentially impact on the lifetime risk for breast cancer. Technological advances over the past years have enabled the detection of genetic risk factors through high-throughput screening of large breast cancer case-control series. High- to intermediate penetrance alleles have now been identified in more than 20 genes involved in DNA damage signalling and repair, and more than 70 low-penetrance loci have been discovered through recent genome-wide association studies. In addition to classical germ-line mutation and single-nucleotide polymorphism, copy number variation and somatic mosaicism have been proposed as potential predisposing mechanisms. Many of the identified loci also appear to influence breast tumour characteristics such as estrogen receptor status. In this review, we briefly summarize present knowledge about breast cancer susceptibility genes and discuss their implications for risk prediction and clinical practice. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 25% |
| India | 1 | 25% |
| Unknown | 2 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 107 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | <1% |
| Portugal | 1 | <1% |
| Russia | 1 | <1% |
| Unknown | 104 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 16 | 15% |
| Student > Master | 15 | 14% |
| Student > Bachelor | 13 | 12% |
| Student > Ph. D. Student | 10 | 9% |
| Professor > Associate Professor | 7 | 7% |
| Other | 16 | 15% |
| Unknown | 30 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 25 | 23% |
| Medicine and Dentistry | 23 | 21% |
| Biochemistry, Genetics and Molecular Biology | 17 | 16% |
| Social Sciences | 2 | 2% |
| Mathematics | 1 | <1% |
| Other | 7 | 7% |
| Unknown | 32 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2016.
All research outputs
#15,740,207
of 25,374,647 outputs
Outputs from Hereditary Cancer in Clinical Practice
#112
of 260 outputs
Outputs of similar age
#118,711
of 210,822 outputs
Outputs of similar age from Hereditary Cancer in Clinical Practice
#2
of 5 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 260 research outputs from this source. They receive a mean Attention Score of 4.8. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,822 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.