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Identification of key structural elements for neuronal calcium sensor-1 function in the regulation of the temperature-dependency of locomotion in C. elegans

Overview of attention for article published in Molecular Brain, August 2013
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  • Above-average Attention Score compared to outputs of the same age and source (62nd percentile)

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2 X users

Citations

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Title
Identification of key structural elements for neuronal calcium sensor-1 function in the regulation of the temperature-dependency of locomotion in C. elegans
Published in
Molecular Brain, August 2013
DOI 10.1186/1756-6606-6-39
Pubmed ID
Authors

Victoria M Martin, James R Johnson, Lee P Haynes, Jeff W Barclay, Robert D Burgoyne

Abstract

Intracellular Ca2+ regulates many aspects of neuronal function through Ca2+ binding to EF hand-containing Ca2+ sensors that in turn bind target proteins to regulate their function. Amongst the sensors are the neuronal calcium sensor (NCS) family of proteins that are involved in multiple neuronal signalling pathways. Each NCS protein has specific and overlapping targets and physiological functions and specificity is likely to be determined by structural features within the proteins. Common to the NCS proteins is the exposure of a hydrophobic groove, allowing target binding in the Ca2+-loaded form. Structural analysis of NCS protein complexes with target peptides has indicated common and distinct aspects of target protein interaction. Two key differences between NCS proteins are the size of the hydrophobic groove that is exposed for interaction and the role of their non-conserved C-terminal tails.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 6%
United States 1 6%
Brazil 1 6%
Unknown 14 82%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 29%
Student > Ph. D. Student 5 29%
Student > Master 2 12%
Student > Postgraduate 1 6%
Unspecified 1 6%
Other 0 0%
Unknown 3 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 29%
Pharmacology, Toxicology and Pharmaceutical Science 2 12%
Neuroscience 2 12%
Psychology 2 12%
Mathematics 1 6%
Other 2 12%
Unknown 3 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 July 2014.
All research outputs
#17,696,782
of 22,721,584 outputs
Outputs from Molecular Brain
#745
of 1,103 outputs
Outputs of similar age
#143,744
of 200,141 outputs
Outputs of similar age from Molecular Brain
#3
of 8 outputs
Altmetric has tracked 22,721,584 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,103 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 200,141 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.