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The splice site variant rs11078928 may be associated with a genotype-dependent alteration in expression of GSDMB transcripts

Overview of attention for article published in BMC Genomics, September 2013
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2 X users

Citations

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36 Mendeley
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Title
The splice site variant rs11078928 may be associated with a genotype-dependent alteration in expression of GSDMB transcripts
Published in
BMC Genomics, September 2013
DOI 10.1186/1471-2164-14-627
Pubmed ID
Authors

Faer S Morrison, Jonathan M Locke, Andrew R Wood, Marcus Tuke, Dorota Pasko, Anna Murray, Tim Frayling, Lorna W Harries

Abstract

Many genetic variants have been associated with susceptibility to complex traits by genome wide association studies (GWAS), but for most, causal genes and mechanisms of action have yet to be elucidated. Using bioinformatics, we identified index and proxy variants associated with autoimmune disease susceptibility, with the potential to affect splicing of candidate genes. PCR and sequence analysis of whole blood RNA samples from population controls was then carried out for the 8 most promising variants to determine the effect of genetic variation on splicing of target genes.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 36 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 19%
Researcher 6 17%
Student > Master 5 14%
Student > Doctoral Student 2 6%
Professor > Associate Professor 2 6%
Other 5 14%
Unknown 9 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 10 28%
Agricultural and Biological Sciences 8 22%
Medicine and Dentistry 6 17%
Immunology and Microbiology 1 3%
Neuroscience 1 3%
Other 1 3%
Unknown 9 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 September 2013.
All research outputs
#17,696,782
of 22,721,584 outputs
Outputs from BMC Genomics
#7,537
of 10,626 outputs
Outputs of similar age
#144,178
of 201,942 outputs
Outputs of similar age from BMC Genomics
#76
of 140 outputs
Altmetric has tracked 22,721,584 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,626 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 23rd percentile – i.e., 23% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 201,942 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 140 others from the same source and published within six weeks on either side of this one. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.