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Neonatal dexamethasone treatment exacerbates hypoxic-ischemic brain injury

Overview of attention for article published in Molecular Brain, April 2013
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Title
Neonatal dexamethasone treatment exacerbates hypoxic-ischemic brain injury
Published in
Molecular Brain, April 2013
DOI 10.1186/1756-6606-6-18
Pubmed ID
Authors

Kan-Hsun Chang, Che-Ming Yeh, Chia-Yu Yeh, Chiung-Chun Huang, Kuei-Sen Hsu

Abstract

The synthetic glucocorticoid dexamethasone (DEX) is commonly used to prevent chronic lung disease in prematurely born infants. Treatment regimens usually consist of high doses of DEX for several weeks, notably during a critical period of brain development. Therefore, there is some concern about adverse effects of this clinical practice on fetal brain development. In this study, using a clinically relevant rat model, we examined the impact of neonatal DEX treatment on subsequent brain injury due to an episode of cerebral hypoxia-ischemia (HI).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
Spain 1 3%
United States 1 3%
Egypt 1 3%
Unknown 32 89%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 22%
Researcher 7 19%
Student > Master 6 17%
Student > Bachelor 2 6%
Lecturer 2 6%
Other 7 19%
Unknown 4 11%
Readers by discipline Count As %
Medicine and Dentistry 8 22%
Agricultural and Biological Sciences 8 22%
Neuroscience 8 22%
Psychology 2 6%
Nursing and Health Professions 1 3%
Other 4 11%
Unknown 5 14%