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Carbon dots as fluorescent probes for “off–on” detection of Cu2+ and l-cysteine in aqueous solution

Overview of attention for article published in Biosensors & Bioelectronics, January 2014
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  • Above-average Attention Score compared to outputs of the same age (57th percentile)
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Mentioned by

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5 tweeters

Citations

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158 Dimensions

Readers on

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65 Mendeley
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Title
Carbon dots as fluorescent probes for “off–on” detection of Cu2+ and l-cysteine in aqueous solution
Published in
Biosensors & Bioelectronics, January 2014
DOI 10.1016/j.bios.2013.07.042
Pubmed ID
Authors

Jie Zong, Xiaoling Yang, Adrian Trinchi, Simon Hardin, Ivan Cole, Yihua Zhu, Chunzhong Li, Tim Muster, Gang Wei

Abstract

Copper ion (Cu(2+)) and L-cysteine (L-Cys) detection is critically important since an abnormal level of Cu(2+) or L-Cys is an indicator for many diseases. In this paper, we demonstrate an "off-on" approach for highly sensitive and selective detection of Cu(2+) and L-Cys using carbon dots (CDs) as fluorescent probes. CDs were prepared by using mesoporous silica (MS) spheres as nanoreactors. The binding ability of CDs towards metal ions was examined by comparing the fluorescence intensities of CDs before and after the addition of the metal ions. The addition of Cu(2+) cations leads to their absorption on the surface of CDs and the significant fluorescence quench of CDs (turn-off). The resulting in CDs-Cu(2+) system was found to be sensitive to L-Cys. The addition of L-Cys not only serves to shelter the CDs effectively from being quenched, but also to reverse the quenching and restore the fluorescence (turn-on) due to its ability to remove Cu(2+) from the surface of CDs. This method is facile, rapid, low cost, and environment-friendly. A detection limit as low as 2.3×10(-8) M for Cu(2+) and 3.4×10(-10) M for L-Cys is obtained, which is promising for biological applications.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 65 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 19 29%
Student > Master 14 22%
Student > Doctoral Student 7 11%
Researcher 5 8%
Student > Bachelor 5 8%
Other 12 18%
Unknown 3 5%
Readers by discipline Count As %
Chemistry 33 51%
Engineering 6 9%
Chemical Engineering 5 8%
Agricultural and Biological Sciences 4 6%
Materials Science 3 5%
Other 5 8%
Unknown 9 14%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 August 2013.
All research outputs
#6,705,513
of 12,369,686 outputs
Outputs from Biosensors & Bioelectronics
#2,262
of 4,345 outputs
Outputs of similar age
#65,220
of 158,904 outputs
Outputs of similar age from Biosensors & Bioelectronics
#23
of 36 outputs
Altmetric has tracked 12,369,686 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,345 research outputs from this source. They receive a mean Attention Score of 3.6. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 158,904 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.