Title |
Characterizing the normal proteome of human ciliary body
|
---|---|
Published in |
Clinical Proteomics, August 2013
|
DOI | 10.1186/1559-0275-10-9 |
Pubmed ID | |
Authors |
Renu Goel, Krishna R Murthy, Srinivas M Srikanth, Sneha M Pinto, Mitali Bhattacharjee, Dhanashree S Kelkar, Anil K Madugundu, Gourav Dey, Sujatha S Mohan, Venkatarangaiah Krishna, TS Keshava Prasad, Shukti Chakravarti, HC Harsha, Akhilesh Pandey |
Abstract |
The ciliary body is the circumferential muscular tissue located just behind the iris in the anterior chamber of the eye. It plays a pivotal role in the production of aqueous humor, maintenance of the lens zonules and accommodation by changing the shape of the crystalline lens. The ciliary body is the major target of drugs against glaucoma as its inhibition leads to a drop in intraocular pressure. A molecular study of the ciliary body could provide a better understanding about the pathophysiological processes that occur in glaucoma. Thus far, no large-scale proteomic investigation has been reported for the human ciliary body. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 34 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 7 | 21% |
Student > Bachelor | 5 | 15% |
Student > Ph. D. Student | 4 | 12% |
Other | 2 | 6% |
Professor | 2 | 6% |
Other | 6 | 18% |
Unknown | 8 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 8 | 24% |
Biochemistry, Genetics and Molecular Biology | 7 | 21% |
Agricultural and Biological Sciences | 3 | 9% |
Neuroscience | 2 | 6% |
Engineering | 2 | 6% |
Other | 3 | 9% |
Unknown | 9 | 26% |