Title |
Is carbohydrate needed to further stimulate muscle protein synthesis/hypertrophy following resistance exercise?
|
---|---|
Published in |
Journal of the International Society of Sports Nutrition, April 2022
|
DOI | 10.1186/1550-2783-10-42 |
Pubmed ID | |
Authors |
Vandré Casagrande Figueiredo, David Cameron-Smith |
Abstract |
It is now well established that protein supplementation after resistance exercise promotes increased muscle protein synthesis, which ultimately results in greater net muscle accretion, relative to exercise alone or exercise with supplementary carbohydrate ingestion. However, it is not known whether combining carbohydrate with protein produces a greater anabolic response than protein alone. Recent recommendations have been made that the composition of the ideal supplement post-exercise would be a combination of a protein source with a high glycemic index carbohydrate. This is based on the hypothesis that insulin promotes protein synthesis, thus maximising insulin secretion will maximally potentiate this action. However, it is still controversial as to whether raising insulin level, within the physiological range, has any effect to further stimulate muscle protein synthesis. The present commentary will review the evidence underpinning the recommendation to consume carbohydrates in addition to a protein supplementation after resistance exercise for the specific purpose of increasing muscle mass. The paucity of data will be discussed, thus our conclusions are that further studies are necessary prior to any conclusions that enable evidence-based recommendations to be made. |
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Geographical breakdown
Country | Count | As % |
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United Kingdom | 35 | 20% |
United States | 27 | 16% |
Spain | 16 | 9% |
Canada | 7 | 4% |
Brazil | 5 | 3% |
Australia | 4 | 2% |
South Africa | 3 | 2% |
Sweden | 3 | 2% |
Norway | 2 | 1% |
Other | 12 | 7% |
Unknown | 60 | 34% |
Demographic breakdown
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Members of the public | 109 | 63% |
Practitioners (doctors, other healthcare professionals) | 42 | 24% |
Scientists | 22 | 13% |
Science communicators (journalists, bloggers, editors) | 1 | <1% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 5 | 3% |
United States | 2 | 1% |
New Zealand | 1 | <1% |
Portugal | 1 | <1% |
Spain | 1 | <1% |
Denmark | 1 | <1% |
Unknown | 175 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 43 | 23% |
Student > Master | 32 | 17% |
Other | 19 | 10% |
Student > Ph. D. Student | 15 | 8% |
Student > Postgraduate | 13 | 7% |
Other | 39 | 21% |
Unknown | 25 | 13% |
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Agricultural and Biological Sciences | 32 | 17% |
Medicine and Dentistry | 30 | 16% |
Nursing and Health Professions | 16 | 9% |
Biochemistry, Genetics and Molecular Biology | 12 | 6% |
Other | 15 | 8% |
Unknown | 31 | 17% |