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Change in mRNA expression of sirtuin 1 and sirtuin 3 in cats fed on high fat diet

Overview of attention for article published in BMC Veterinary Research, September 2013
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  • Above-average Attention Score compared to outputs of the same age and source (61st percentile)

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Citations

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Title
Change in mRNA expression of sirtuin 1 and sirtuin 3 in cats fed on high fat diet
Published in
BMC Veterinary Research, September 2013
DOI 10.1186/1746-6148-9-187
Pubmed ID
Authors

Shingo Ishikawa, Gebin Li, Hiroshi Takemitsu, Megumi Fujiwara, Nobuko Mori, Ichiro Yamamoto, Toshiro Arai

Abstract

Mammalian sirtuins are homologs to the yeast silent information regulator 2 (Sir2), which is an NAD-dependent deacetylase. Sirtuins are comprised of 7 proteins, and each has different target proteins. Sirtuin 1 (SIRT1) plays important roles in maintaining metabolic functions and immune responses, and SIRT3 protects cells from oxidative stress-induced cell death. Both SIRT1 and SIRT3 are regulated by metabolic status and aging. Hence, SIRT1 and SIRT3 have been researched in metabolic diseases, such as type 2 diabetes mellitus (DM), fatty liver, and heart diseases. Although these diseases have been increasing, there is little information about relation between the diseases and SIRT1 and SIRT3 in cats. Therefore we cloned SIRT1 and SIRT3 cDNA, examined mRNA expression in cat tissues, and investigated the changes in SIRT1 and SIRT3 mRNA expression in peripheral blood leukocyte of cats fed on HFD for 6 weeks.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Brazil 1 3%
Unknown 34 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 28%
Student > Master 6 17%
Researcher 5 14%
Student > Bachelor 4 11%
Librarian 1 3%
Other 2 6%
Unknown 8 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 31%
Biochemistry, Genetics and Molecular Biology 6 17%
Medicine and Dentistry 4 11%
Veterinary Science and Veterinary Medicine 2 6%
Arts and Humanities 1 3%
Other 2 6%
Unknown 10 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 November 2014.
All research outputs
#14,102,908
of 23,881,329 outputs
Outputs from BMC Veterinary Research
#968
of 3,087 outputs
Outputs of similar age
#110,027
of 207,062 outputs
Outputs of similar age from BMC Veterinary Research
#11
of 26 outputs
Altmetric has tracked 23,881,329 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,087 research outputs from this source. They receive a mean Attention Score of 4.2. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 207,062 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.