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RNA Interference

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Cover of 'RNA Interference'

Table of Contents

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    Book Overview
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    Chapter 1 RNA interference: mechanisms, technical challenges, and therapeutic opportunities.
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    Chapter 2 Nanostructured RNAs for RNA Interference
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    Chapter 3 One Long Oligonucleotide or Two Short Oligonucleotides Based shRNA Construction and Expression
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    Chapter 4 PLGA Microspheres Encapsulating siRNA
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    Chapter 5 Magnetic Nanoparticle and Magnetic Field Assisted siRNA Delivery In Vitro
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    Chapter 6 Cytoplasmic Delivery of siRNAs to Monocytes and Dendritic Cells via Electroporation
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    Chapter 7 Delivery of siRNAs to Cancer Cells via Bacteria
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    Chapter 8 Microwell array-mediated delivery of lipoplexes containing nucleic acids for enhanced therapeutic efficacy.
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    Chapter 9 Modulating the Tumor Microenvironment with RNA Interference as a Cancer Treatment Strategy
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    Chapter 10 Targeted In Vivo Delivery of siRNA and an Endosome-Releasing Agent to Hepatocytes.
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    Chapter 11 Cell-Internalization SELEX: Method for Identifying Cell-Internalizing RNA Aptamers for Delivering siRNAs to Target Cells.
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    Chapter 12 Strategies for siRNA Navigation to Desired Cells.
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    Chapter 13 Use of Guanidinopropyl-Modified siRNAs to Silence Gene Expression
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    Chapter 14 Therapy of Respiratory Viral Infections with Intranasal siRNAs
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    Chapter 15 Engineering therapeutic cancer vaccines that activate antitumor immunity.
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    Chapter 16 Immunosuppressive Factor Blockade in Dendritic Cells via siRNAs Results in Objective Clinical Responses.
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    Chapter 17 Targeting bcr-abl Transcripts with siRNAs in an Imatinib-Resistant Chronic Myeloid Leukemia Patient: Challenges and Future Directions.
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    Chapter 18 A facile method for interfering with off-target silencing mediated by the sense strand.
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    Chapter 19 Overcoming the Challenges of siRNA Activation of Innate Immunity: Design Better Therapeutic siRNAs.
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    Chapter 20 Gene Silencing In Vitro and In Vivo Using Intronic MicroRNAs.
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    Chapter 21 In Silico Identification of Novel Endo-siRNAs.
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    Chapter 22 Computer-Assisted Annotation of Small RNA Transcriptomes
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    Chapter 23 miR-CATCH: MicroRNA Capture Affinity Technology.
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    Chapter 24 Roles of MicroRNAs in Cancers and Development.
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    Chapter 25 Targeting MicroRNAs to Withstand Cancer Metastasis.
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    Chapter 26 Urinary MicroRNAs as a New Class of Noninvasive Biomarkers in Oncology, Nephrology, and Cardiology.
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    Chapter 27 Magnetic Bead-Based Isolation of Exosomes
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    Chapter 28 Modified 2'-Ribose Small RNAs Function as Toll-Like Receptor-7/8 Antagonists.
Attention for Chapter 22: Computer-Assisted Annotation of Small RNA Transcriptomes
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