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Application of prognostic score IPSET-thrombosis in patients with essential thrombocythemia of a Brazilian public service

Overview of attention for article published in Revista da Associação Médica Brasileira, October 2016
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (58th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

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1 policy source

Citations

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1 Dimensions

Readers on

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20 Mendeley
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Title
Application of prognostic score IPSET-thrombosis in patients with essential thrombocythemia of a Brazilian public service
Published in
Revista da Associação Médica Brasileira, October 2016
DOI 10.1590/1806-9282.62.07.647
Pubmed ID
Authors

Luana Magalhães Navarro, Damila Cristina Trufelli, Debora Rodrigues Bonito, Auro Del Giglio, Patricia Weinschenker Bollmann

Abstract

In patients with essential thrombocythemia (ET), the vascular complications contribute to morbidity and mortality. To better predict the occurrence of thrombotic events, an International Prognostic Score for Thrombosis in Essential Thrombocythemia (IPSET-thrombosis) has recently been proposed. We present the application of this score and compare its results with the usual classification system. We retrospectively evaluated the characteristics and risk factors for thrombosis of 46 patients with a diagnosis of ET seen in the last 6 years at Faculdade de Medicina do ABC (FMABC). Thrombosis in the arterial territory was more prevalent than in venous sites. We observed that cardiovascular risk factors (hypertension, hypercholesterolemia, diabetes mellitus, and smoking) were also risk factors for thrombosis (p<0.001). Age over 60 years and presence of JAK2 V617F mutation were not associated with the occurrence of thrombotic events. No patient classified by IPSET-thrombosis as low risk had a thrombotic event. Furthermore, using the IPSET-thrombosis scale, we identified two patients who had thrombotic events during follow-up and were otherwise classified in the low-risk group of the traditional classification. Leukocytosis at diagnosis was significantly associated with arterial thrombosis (p=0.02), while splenomegaly was associated with venous thrombotic events (p=0.01). Cardiovascular risk factors and leukocytosis were directly associated with arterial thrombosis. IPSET-thrombosis appears to be better than the traditional classification at identifying lower risk patients who do not need specific therapy.

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 3 15%
Student > Bachelor 3 15%
Unspecified 2 10%
Student > Master 2 10%
Student > Ph. D. Student 2 10%
Other 4 20%
Unknown 4 20%
Readers by discipline Count As %
Medicine and Dentistry 4 20%
Psychology 2 10%
Unspecified 2 10%
Social Sciences 1 5%
Biochemistry, Genetics and Molecular Biology 1 5%
Other 2 10%
Unknown 8 40%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 March 2018.
All research outputs
#5,609,060
of 17,364,317 outputs
Outputs from Revista da Associação Médica Brasileira
#87
of 674 outputs
Outputs of similar age
#103,883
of 273,378 outputs
Outputs of similar age from Revista da Associação Médica Brasileira
#1
of 10 outputs
Altmetric has tracked 17,364,317 research outputs across all sources so far. This one is in the 47th percentile – i.e., 47% of other outputs scored the same or lower than it.
So far Altmetric has tracked 674 research outputs from this source. They receive a mean Attention Score of 2.7. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 273,378 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them