Title |
Human Polyomavirus JC monitoring and noncoding control region analysis in dynamic cohorts of individuals affected by immune-mediated diseases under treatment with biologics: an observational study
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Published in |
Virology Journal, September 2013
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DOI | 10.1186/1743-422x-10-298 |
Pubmed ID | |
Authors |
Anna Bellizzi, Elena Anzivino, Donatella Maria Rodio, Sara Cioccolo, Rossana Scrivo, Manuela Morreale, Simona Pontecorvo, Federica Ferrari, Giovanni Di Nardo, Lucia Nencioni, Silvia Carluccio, Guido Valesini, Ada Francia, Salvatore Cucchiara, Anna Teresa Palamara, Valeria Pietropaolo |
Abstract |
Progressive multifocal leukoencephalopathy (PML) onset, caused by Polyomavirus JC (JCPyV) in patients affected by immune-mediated diseases during biological treatment, raised concerns about the safety profile of these agents. Therefore, the aims of this study were the JCPyV reactivation monitoring and the noncoding control region (NCCR) and viral protein 1 (VP1) analysis in patients affected by different immune-mediated diseases and treated with biologics. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 2% |
Unknown | 52 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 9 | 17% |
Student > Master | 9 | 17% |
Student > Bachelor | 6 | 11% |
Student > Doctoral Student | 5 | 9% |
Professor > Associate Professor | 4 | 8% |
Other | 11 | 21% |
Unknown | 9 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 17 | 32% |
Psychology | 4 | 8% |
Agricultural and Biological Sciences | 4 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 6% |
Immunology and Microbiology | 3 | 6% |
Other | 11 | 21% |
Unknown | 11 | 21% |