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Saturable human neopterin response to interferon-α assessed by a pharmacokinetic-pharmacodynamic model

Overview of attention for article published in Journal of Translational Medicine, October 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (66th percentile)
  • Good Attention Score compared to outputs of the same age and source (68th percentile)

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1 X user
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2 patents

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19 Mendeley
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Title
Saturable human neopterin response to interferon-α assessed by a pharmacokinetic-pharmacodynamic model
Published in
Journal of Translational Medicine, October 2013
DOI 10.1186/1479-5876-11-240
Pubmed ID
Authors

Sangil Jeon, Jae-Hyeon Juhn, Seunghoon Han, Jongtae Lee, Taegon Hong, Jeongki Paek, Dong-Seok Yim

Abstract

In this study, we developed a pharmacokinetic (PK)- pharmacodynamic (PD) model of a new sustained release formulation of interferon-α-2a (SR-IFN-α) using the blood concentration of IFN-α and neopterin in order to quantify the magnitude and saturation of neopterin production over time in healthy volunteers. The SR-IFN-α in this study is a solid microparticular formulation manufactured by spray drying of a feeding solution containing IFN-α, a biocompatible polymer (polyethylene glycol) and sodium hyaluronate.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 5%
Unknown 18 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 32%
Student > Master 2 11%
Unspecified 1 5%
Student > Doctoral Student 1 5%
Librarian 1 5%
Other 2 11%
Unknown 6 32%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 3 16%
Medicine and Dentistry 3 16%
Biochemistry, Genetics and Molecular Biology 2 11%
Immunology and Microbiology 2 11%
Agricultural and Biological Sciences 1 5%
Other 2 11%
Unknown 6 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 June 2023.
All research outputs
#7,185,533
of 22,711,242 outputs
Outputs from Journal of Translational Medicine
#1,153
of 3,972 outputs
Outputs of similar age
#66,485
of 207,283 outputs
Outputs of similar age from Journal of Translational Medicine
#17
of 67 outputs
Altmetric has tracked 22,711,242 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 3,972 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 207,283 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.