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Approval and Withdrawal of New Antibiotics and other Antiinfectives in the U.S., 1980–2009

Overview of attention for article published in Journal of Law, Medicine & Ethics, January 2021
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#37 of 866)
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Mentioned by

news
1 news outlet
blogs
2 blogs
twitter
8 tweeters

Citations

dimensions_citation
28 Dimensions

Readers on

mendeley
53 Mendeley
citeulike
2 CiteULike
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Title
Approval and Withdrawal of New Antibiotics and other Antiinfectives in the U.S., 1980–2009
Published in
Journal of Law, Medicine & Ethics, January 2021
DOI 10.1111/jlme.12079
Pubmed ID
Authors

Kevin Outterson, John H. Powers, Enrique Seoane-Vazquez, Rosa Rodriguez-Monguio, Aaron S. Kesselheim

Abstract

Numerous reports have noted decreasing numbers of antibiotic approvals. To determine the context for this decline, we examined all new molecule entities (NMEs) and new biologic licenses (NBLs) approved by the FDA from 1980-2009, and compared approval rates of the 61 approved antibiotics to trends in other drug classes. We also tracked withdrawals of approved drugs and found more withdrawals for antibiotics than other drug classes. After adjusting for drugs subsequently withdrawn, the record for antibiotic innovation is less dire than previously reported. We also report problems with the quality of the approved antibiotics studied. Future policies providing incentives for new antibiotic development should not be based on simple numerical targets and key provisions should ensure appropriate quality as well as quantity of antibiotic drug innovation.

Twitter Demographics

The data shown below were collected from the profiles of 8 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 2%
Unknown 52 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 15 28%
Researcher 12 23%
Student > Ph. D. Student 7 13%
Student > Bachelor 5 9%
Student > Doctoral Student 4 8%
Other 8 15%
Unknown 2 4%
Readers by discipline Count As %
Medicine and Dentistry 16 30%
Agricultural and Biological Sciences 11 21%
Chemistry 4 8%
Business, Management and Accounting 3 6%
Immunology and Microbiology 3 6%
Other 10 19%
Unknown 6 11%

Attention Score in Context

This research output has an Altmetric Attention Score of 29. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 October 2017.
All research outputs
#654,278
of 14,514,075 outputs
Outputs from Journal of Law, Medicine & Ethics
#37
of 866 outputs
Outputs of similar age
#8,788
of 167,565 outputs
Outputs of similar age from Journal of Law, Medicine & Ethics
#3
of 21 outputs
Altmetric has tracked 14,514,075 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 866 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 167,565 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.