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Plasticity of primary microglia on micropatterned geometries and spontaneous long-distance migration in microfluidic channels

Overview of attention for article published in BMC Neuroscience, January 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

blogs
1 blog
twitter
2 tweeters
googleplus
1 Google+ user

Citations

dimensions_citation
14 Dimensions

Readers on

mendeley
39 Mendeley
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Title
Plasticity of primary microglia on micropatterned geometries and spontaneous long-distance migration in microfluidic channels
Published in
BMC Neuroscience, January 2013
DOI 10.1186/1471-2202-14-121
Pubmed ID
Authors

Susanna Amadio, Adele De Ninno, Cinzia Montilli, Luca Businaro, Annamaria Gerardino, Cinzia Volonté

Abstract

Microglia possess an elevated grade of plasticity, undergoing several structural changes based on their location and state of activation. The first step towards the comprehension of microglia's biology and functional responses to an extremely mutable extracellular milieu, consists in discriminating the morphological features acquired by cells maintained in vitro under diverse environmental conditions. Previous work described neither primary microglia grown on artificially patterned environments which impose physical cues and constraints, nor long distance migration of microglia in vitro. To this aim, the present work exploits artificial bio-mimetic microstructured substrates with pillar-shaped or line-grating geometries fabricated on poly(dimethylsiloxane) by soft lithography, in addition to microfluidic devices, and highlights some morphological/functional characteristics of microglia which were underestimated or unknown so far.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 3%
Unknown 38 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 31%
Student > Master 9 23%
Student > Doctoral Student 8 21%
Student > Ph. D. Student 6 15%
Student > Bachelor 2 5%
Other 2 5%
Readers by discipline Count As %
Neuroscience 9 23%
Biochemistry, Genetics and Molecular Biology 7 18%
Agricultural and Biological Sciences 7 18%
Engineering 4 10%
Medicine and Dentistry 4 10%
Other 5 13%
Unknown 3 8%

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 October 2013.
All research outputs
#946,812
of 8,231,858 outputs
Outputs from BMC Neuroscience
#84
of 833 outputs
Outputs of similar age
#17,777
of 144,117 outputs
Outputs of similar age from BMC Neuroscience
#2
of 47 outputs
Altmetric has tracked 8,231,858 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 833 research outputs from this source. They receive a mean Attention Score of 3.6. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 144,117 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 47 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.