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Colloidal Gold Nanoclusters Spiked Silica Fillers in Mixed Matrix Coatings: Simultaneous Detection and Inhibition of Healthcare-Associated Infections

Overview of attention for article published in Advanced Healthcare Materials, January 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

news
3 news outlets
blogs
1 blog

Citations

dimensions_citation
14 Dimensions

Readers on

mendeley
23 Mendeley
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Title
Colloidal Gold Nanoclusters Spiked Silica Fillers in Mixed Matrix Coatings: Simultaneous Detection and Inhibition of Healthcare-Associated Infections
Published in
Advanced Healthcare Materials, January 2017
DOI 10.1002/adhm.201601135
Pubmed ID
Authors

Shahad K. Alsaiari, Mohammed A. Hammami, Jonas G. Croissant, Haneen W. Omar, Pradeep Neelakanda, Tahir Yapici, Klaus-Viktor Peinemann, Niveen M. Khashab

Abstract

Healthcare-associated infections (HAIs) are the infections that patients get while receiving medical treatment in a medical facility with bacterial HAIs being the most common. Silver and gold nanoparticles (NPs) have been successfully employed as antibacterial motifs; however, NPs leaching in addition to poor dispersion and overall reproducibility are major hurdles to further product development. In this study, the authors design and fabricate a smart antibacterial mixed-matrix membrane coating comprising colloidal lysozyme-templated gold nanoclusters as nanofillers in poly(ethylene oxide)/poly(butylene terephthalate) amphiphilic polymer matrix. Mesoporous silica nanoparticles-lysozyme functionalized gold nanoclusters disperse homogenously within the polymer matrix with no phase separation and zero NPs leaching. This mixed-matrix coating can successfully sense and inhibit bacterial contamination via a controlled release mechanism that is only triggered by bacteria. The system is coated on a common radiographic dental imaging device (photostimulable phosphor plate) that is prone to oral bacteria contamination. Variation and eventually disappearance of the red fluorescence surface under UV light signals bacterial infection. Kanamycin, an antimicrobial agent, is controllably released to instantly inhibit bacterial growth. Interestingly, the quality of the images obtained with these coated surfaces is the same as uncoated surfaces and thus the safe application of such smart coatings can be expanded to include other medical devices without compromising their utility.

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Saudi Arabia 1 4%
Unknown 22 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 30%
Student > Master 5 22%
Other 2 9%
Student > Ph. D. Student 2 9%
Unknown 7 30%
Readers by discipline Count As %
Materials Science 4 17%
Agricultural and Biological Sciences 3 13%
Environmental Science 2 9%
Chemistry 2 9%
Medicine and Dentistry 1 4%
Other 2 9%
Unknown 9 39%

Attention Score in Context

This research output has an Altmetric Attention Score of 27. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 July 2017.
All research outputs
#622,100
of 13,530,222 outputs
Outputs from Advanced Healthcare Materials
#65
of 1,350 outputs
Outputs of similar age
#22,464
of 264,404 outputs
Outputs of similar age from Advanced Healthcare Materials
#7
of 60 outputs
Altmetric has tracked 13,530,222 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,350 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,404 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 60 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.