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Stem cell transplantation therapy for multifaceted therapeutic benefits after stroke

Overview of attention for article published in Progress in Neurobiology, October 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • Good Attention Score compared to outputs of the same age and source (70th percentile)

Mentioned by

blogs
1 blog
twitter
4 tweeters
facebook
1 Facebook page

Citations

dimensions_citation
42 Dimensions

Readers on

mendeley
60 Mendeley
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Title
Stem cell transplantation therapy for multifaceted therapeutic benefits after stroke
Published in
Progress in Neurobiology, October 2017
DOI 10.1016/j.pneurobio.2017.03.003
Pubmed ID
Authors

Ling Wei, Zheng Z. Wei, Michael Qize Jiang, Osama Mohamad, Shan Ping Yu

Abstract

One of the exciting advances in modern medicine and life science is cell-based neurovascular regeneration of damaged brain tissues and repair of neuronal structures. The progress in stem cell biology and creation of adult induced pluripotent stem (iPS) cells has significantly improved basic and pre-clinical research in disease mechanisms and generated enthusiasm for potential applications in the treatment of central nervous system (CNS) diseases including stroke. Endogenous neural stem cells and cultured stem cells are capable of self-renewal and give rise to virtually all types of cells essential for the makeup of neuronal structures. Meanwhile, stem cells and neural progenitor cells are well-known for their potential for trophic support after transplantation into the ischemic brain. Thus, stem cell-based therapies provide an attractive future for protecting and repairing damaged brain tissues after injury and in various disease states. Moreover, basic research on naïve and differentiated stem cells including iPS cells has markedly improved our understanding of cellular and molecular mechanisms of neurological disorders, and provides a platform for the discovery of novel drug targets. The latest advances indicate that combinatorial approaches using cell based therapy with additional treatments such as protective reagents, preconditioning strategies and rehabilitation therapy can significantly improve therapeutic benefits. In this review, we will discuss the characteristics of cell therapy in different ischemic models and the application of stem cells and progenitor cells as regenerative medicine for the treatment of stroke.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Russia 1 2%
Unknown 58 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 15 25%
Student > Master 10 17%
Researcher 9 15%
Student > Ph. D. Student 7 12%
Student > Postgraduate 3 5%
Other 9 15%
Unknown 7 12%
Readers by discipline Count As %
Medicine and Dentistry 14 23%
Neuroscience 9 15%
Biochemistry, Genetics and Molecular Biology 9 15%
Agricultural and Biological Sciences 6 10%
Engineering 3 5%
Other 7 12%
Unknown 12 20%

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 May 2018.
All research outputs
#1,864,469
of 14,360,252 outputs
Outputs from Progress in Neurobiology
#174
of 932 outputs
Outputs of similar age
#52,400
of 263,683 outputs
Outputs of similar age from Progress in Neurobiology
#6
of 20 outputs
Altmetric has tracked 14,360,252 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 932 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,683 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.