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Functional analysis of the rodent CK1tau mutation in the circadian clock of a marine unicellular alga

Overview of attention for article published in BMC Molecular and Cell Biology, October 2013
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  • Above-average Attention Score compared to outputs of the same age and source (53rd percentile)

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Title
Functional analysis of the rodent CK1tau mutation in the circadian clock of a marine unicellular alga
Published in
BMC Molecular and Cell Biology, October 2013
DOI 10.1186/1471-2121-14-46
Pubmed ID
Authors

Gerben van Ooijen, Sarah F Martin, Martin E Barrios-Llerena, Matthew Hindle, Thierry Le Bihan, John S O'Neill, Andrew J Millar

Abstract

Casein Kinase 1 (CK1) is one of few proteins known to affect cellular timekeeping across metazoans, and the naturally occurring CK1tau mutation shortens circadian period in mammals. Functional conservation of a timekeeping function for CK1 in the green lineage was recently identified in the green marine unicell Ostreococcus tauri, in spite of the absence of CK1's transcriptional targets known from other species. The short-period phenotype of CK1tau mutant in mammals depends specifically on increased CK1 activity against PERIOD proteins. To understand how CK1 acts differently upon the algal clock, we analysed the cellular and proteomic effects of CK1tau overexpression in O. tauri.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 31 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 19%
Student > Ph. D. Student 6 19%
Student > Master 5 16%
Student > Bachelor 4 13%
Professor 3 10%
Other 4 13%
Unknown 3 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 39%
Biochemistry, Genetics and Molecular Biology 5 16%
Chemistry 2 6%
Business, Management and Accounting 1 3%
Unspecified 1 3%
Other 2 6%
Unknown 8 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 October 2013.
All research outputs
#16,047,334
of 25,374,647 outputs
Outputs from BMC Molecular and Cell Biology
#700
of 1,233 outputs
Outputs of similar age
#128,649
of 223,875 outputs
Outputs of similar age from BMC Molecular and Cell Biology
#11
of 26 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,233 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 223,875 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.