Title |
Comparative effect of Piper betle, Chlorella vulgaris and tocotrienol-rich fraction on antioxidant enzymes activity in cellular ageing of human diploid fibroblasts
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Published in |
BMC Complementary Medicine and Therapies, August 2013
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DOI | 10.1186/1472-6882-13-210 |
Pubmed ID | |
Authors |
Suzana Makpol, Thong Wei Yeoh, Farah Adilah Che Ruslam, Khaizurin Tajul Arifin, Yasmin Anum Mohd Yusof |
Abstract |
Human diploid fibroblasts (HDFs) undergo a limited number of cellular divisions in culture and progressively reach a state of irreversible growth arrest, a process termed cellular ageing. Even though beneficial effects of Piper betle, Chlorella vulgaris and tocotrienol-rich fraction (TRF) have been reported, ongoing studies in relation to ageing is of interest to determine possible protective effects that may reverse the effect of ageing. The aim of this study was to evaluate the effect of P. betle, C. vulgaris and TRF in preventing cellular ageing of HDFs by determining the activity of antioxidant enzymes viz.; catalase, superoxide dismutase (SOD) and glutathione peroxidase. |
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Mendeley readers
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