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Mendeley readers
Attention Score in Context
| Title |
Grape seed proanthocyanidins ameliorate pancreatic beta-cell dysfunction and death in low-dose streptozotocin- and high-carbohydrate/high-fat diet-induced diabetic rats partially by regulating endoplasmic reticulum stress
|
|---|---|
| Published in |
Nutrition & Metabolism, July 2013
|
| DOI | 10.1186/1743-7075-10-51 |
| Pubmed ID | |
| Authors |
Ye Ding, Zhaofeng Zhang, Xiaoqian Dai, Yanfei Jiang, Lei Bao, Yujie Li, Yong Li |
| Abstract |
It is increasingly being realized that failure of pancreatic beta cells to secrete enough insulin to adequately compensate for obesity and insulin resistance is the primary defects of type 2 diabetes mellitus (T2DM). Pancreatic beta cells possess a highly developed and active endoplasmic reticulum (ER), reflecting their role in folding, export and processing of newly synthesized insulin. ER stress-induced pancreatic beta-cell failure is a novel event in the pathogenesis of T2DM. Some studies with antioxidants indicated a beneficial impact on ER stress. Our previous study found that strong antioxidants, grape seed proanthocyanidins (GSPs), ameliorated ER stress to protect skeletal muscle from cell death in type 2 diabetic rats. The present study continued to investigate the effect of GSPs on beta-cell failure and ER stress in diabetic pancreas. |
Mendeley readers
The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Unknown | 56 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 9 | 16% |
| Student > Master | 8 | 14% |
| Student > Ph. D. Student | 7 | 12% |
| Student > Bachelor | 6 | 11% |
| Student > Doctoral Student | 6 | 11% |
| Other | 9 | 16% |
| Unknown | 12 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 11 | 19% |
| Biochemistry, Genetics and Molecular Biology | 9 | 16% |
| Medicine and Dentistry | 8 | 14% |
| Chemistry | 3 | 5% |
| Social Sciences | 3 | 5% |
| Other | 8 | 14% |
| Unknown | 15 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 October 2013.
All research outputs
#20,207,295
of 22,727,570 outputs
Outputs from Nutrition & Metabolism
#846
of 944 outputs
Outputs of similar age
#173,525
of 197,455 outputs
Outputs of similar age from Nutrition & Metabolism
#3
of 4 outputs
Altmetric has tracked 22,727,570 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 944 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 197,455 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.