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Increased plasma arginase activity in human sepsis: association with increased circulating neutrophils

Overview of attention for article published in Clinical Chemistry and Laboratory Medicine, January 2014
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Title
Increased plasma arginase activity in human sepsis: association with increased circulating neutrophils
Published in
Clinical Chemistry and Laboratory Medicine, January 2014
DOI 10.1515/cclm-2013-0698
Pubmed ID
Authors

Christabelle J. Darcy, Tonia Woodberry, Joshua S. Davis, Kim A. Piera, Yvette R. McNeil, Youwei Chen, Tsin W. Yeo, J. Brice Weinberg, Nicholas M. Anstey

Abstract

The pathophysiology of sepsis is incompletely understood. Impaired bioavailability of L-arginine, the substrate for NO synthesis, is linked to sepsis severity, and plasma arginase has been linked to hypoargininemia in other disease states. Circulating neutrophils are increased in sepsis and constitutively express arginase. We investigated whether plasma arginase activity is increased in human sepsis and whether this is associated with neutrophil numbers and activation.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 7 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 1 14%
Unknown 6 86%

Demographic breakdown

Readers by professional status Count As %
Unspecified 2 29%
Student > Ph. D. Student 2 29%
Student > Master 2 29%
Lecturer 1 14%
Readers by discipline Count As %
Medicine and Dentistry 3 43%
Agricultural and Biological Sciences 2 29%
Unspecified 2 29%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 October 2013.
All research outputs
#9,998,147
of 12,491,162 outputs
Outputs from Clinical Chemistry and Laboratory Medicine
#900
of 1,656 outputs
Outputs of similar age
#121,305
of 177,077 outputs
Outputs of similar age from Clinical Chemistry and Laboratory Medicine
#3
of 30 outputs
Altmetric has tracked 12,491,162 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,656 research outputs from this source. They receive a mean Attention Score of 2.0. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
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We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.