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Synthesis of an Orthogonally Protected Polyhydroxylated Cyclopentene froml-Sorbose

Overview of attention for article published in Chemistry - An Asian Journal, July 2016
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  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

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1 tweeter
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1 Facebook page

Citations

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2 Dimensions

Readers on

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3 Mendeley
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Title
Synthesis of an Orthogonally Protected Polyhydroxylated Cyclopentene froml-Sorbose
Published in
Chemistry - An Asian Journal, July 2016
DOI 10.1002/asia.201600736
Pubmed ID
Authors

Daniele Lo Re, Leigh Jones, Ernest Giralt, Paul Murphy

Abstract

The use of l-sorbose in the synthesis of functionalized cyclopentene derivatives was accomplished. These cyclopentene derivatives are related to those found in naturally occurring jatrophane frameworks and in other bioactive compounds. The formation of allyl α-l-sorbopyranoside was a key synthetic step. Regioselective introduction of protecting groups was followed by the hydrolysis of the allyl glycoside to furnish a fully protected acyclic l-sorbose derivative. This acyclic intermediate was subsequently used to give an orthogonally protected polyhydroxylated cyclopentene, which has potential for further synthesis of bioactive compounds. The protected cyclopentene itself showed a clear cytotoxic activity when tested against a panel of human cancer cell lines (HT29, LS174T, SW620, A549, and HeLa cells).

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 3 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 3 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 1 33%
Student > Postgraduate 1 33%
Unspecified 1 33%
Readers by discipline Count As %
Chemistry 2 67%
Unspecified 1 33%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 January 2019.
All research outputs
#7,954,915
of 13,205,256 outputs
Outputs from Chemistry - An Asian Journal
#807
of 3,678 outputs
Outputs of similar age
#140,636
of 263,497 outputs
Outputs of similar age from Chemistry - An Asian Journal
#19
of 105 outputs
Altmetric has tracked 13,205,256 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,678 research outputs from this source. They receive a mean Attention Score of 1.6. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,497 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 105 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.