| Chapter title |
Clinical Pharmacology of the Synthetic Cathinone Mephedrone.
|
|---|---|
| Chapter number | 61 |
| Book title |
Neuropharmacology of New Psychoactive Substances (NPS)
|
| Published in |
Current topics in behavioral neurosciences, January 2016
|
| DOI | 10.1007/7854_2016_61 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-952442-9, 978-3-31-952444-3
|
| Authors |
Esther Papaseit, José Moltó, Robert Muga, Marta Torrens, Rafael de la Torre, Magí Farré, Papaseit, Esther, Moltó, José, Muga, Robert, Torrens, Marta, de la Torre, Rafael, Farré, Magí, Torre, Rafael |
| Abstract |
4-Methyl-N-methylcathinone (mephedrone) is a popular new psychoactive substance (NPS) that is structurally related to the parent compound cathinone, the β-keto analogue of amphetamine. Mephedrone appeared on the street drug market as a substitute for 3,4-methylenedioxy-N-methylamphetamine (MDMA, ecstasy) and was subsequently banned due to the potential health risks associated with its use. Nevertheless, mephedrone continues to be widely consumed among specific populations, with unique patterns of misuse. To date, most information about the biological effects of mephedrone comes from user experiences, epidemiological data, clinical cases, toxicological findings, and animal studies, whilst there are very few data regarding its human pharmacodynamics and pharmacokinetics. This chapter reviews the available published data on patterns of mephedrone use, its acute and chronic effects, and its pharmacokinetic properties. More human research is needed to elucidate the safety, toxicity, and addiction potential of mephedrone and related NPS. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 39 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 7 | 18% |
| Student > Bachelor | 4 | 10% |
| Student > Master | 4 | 10% |
| Other | 3 | 8% |
| Researcher | 3 | 8% |
| Other | 7 | 18% |
| Unknown | 11 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 7 | 18% |
| Neuroscience | 4 | 10% |
| Agricultural and Biological Sciences | 3 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 5% |
| Psychology | 2 | 5% |
| Other | 7 | 18% |
| Unknown | 14 | 36% |