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A modified TALEN-based system for robust generation of knock-out human pluripotent stem cell lines and disease models

Overview of attention for article published in BMC Genomics, November 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

blogs
1 blog
twitter
1 X user
patent
1 patent

Citations

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31 Dimensions

Readers on

mendeley
74 Mendeley
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Title
A modified TALEN-based system for robust generation of knock-out human pluripotent stem cell lines and disease models
Published in
BMC Genomics, November 2013
DOI 10.1186/1471-2164-14-773
Pubmed ID
Authors

Stefan Frank, Boris V Skryabin, Boris Greber

Abstract

Transcription activator-like effector nucleases (TALENs) have emerged as a tool for enabling targeted gene editing and disruption in difficult systems, such as human pluripotent stem cells (hPSCs). The modular architecture of TAL effectors theoretically enables targeting of any genomic locus and several cloning systems for custom TALEN assembly have recently been established. However, there is a lack of versatile TALEN expression systems applicable to hPSCs.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
Germany 1 1%
Italy 1 1%
France 1 1%
United Kingdom 1 1%
Poland 1 1%
Unknown 67 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 28 38%
Student > Ph. D. Student 19 26%
Student > Master 5 7%
Student > Postgraduate 4 5%
Student > Bachelor 4 5%
Other 6 8%
Unknown 8 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 34 46%
Biochemistry, Genetics and Molecular Biology 17 23%
Neuroscience 5 7%
Medicine and Dentistry 4 5%
Engineering 2 3%
Other 3 4%
Unknown 9 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 June 2022.
All research outputs
#2,883,563
of 24,293,076 outputs
Outputs from BMC Genomics
#921
of 10,943 outputs
Outputs of similar age
#26,617
of 220,333 outputs
Outputs of similar age from BMC Genomics
#12
of 152 outputs
Altmetric has tracked 24,293,076 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 10,943 research outputs from this source. They receive a mean Attention Score of 4.8. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 220,333 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 152 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.