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Mouse models for pathogenic African trypanosomes: unravelling the immunology of host-parasite-vector interactions

Overview of attention for article published in Parasite Immunology, July 2011
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Mentioned by

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2 tweeters

Citations

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19 Dimensions

Readers on

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57 Mendeley
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Title
Mouse models for pathogenic African trypanosomes: unravelling the immunology of host-parasite-vector interactions
Published in
Parasite Immunology, July 2011
DOI 10.1111/j.1365-3024.2011.01293.x
Pubmed ID
Authors

S. MAGEZ, G. CALJON

Abstract

African trypanosomiasis is a parasitic disease that affects a variety of mammals, including humans, on the sub-Saharan African continent. To understand the diverse parameters that govern the host-parasite-vector interactions, mouse models for the disease have proven to be a cornerstone. Despite the fact that most trypanosomes cannot be considered natural pathogens for rodents, experimental infections in mice have shed a tremendous amount of light on the general biology of these parasites and their interaction with and evasion of the mammalian immune system. Different aspects including inflammation, vaccine failure, antigenic variation, resistance/sensitivity to normal human serum and the influence of tsetse compounds on parasite transmission have all been addressed using mouse models. In more recent years, the introduction of various 'knock-out' mouse strains has allowed to analyse the implication of various cytokines, particularly TNF, IFNγ and IL-10, in the regulation of parasitaemia and induction of pathological conditions during infection.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 2 4%
Uganda 1 2%
Indonesia 1 2%
Japan 1 2%
Colombia 1 2%
Unknown 51 89%

Demographic breakdown

Readers by professional status Count As %
Student > Master 14 25%
Researcher 13 23%
Student > Ph. D. Student 11 19%
Student > Doctoral Student 5 9%
Professor > Associate Professor 4 7%
Other 10 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 28 49%
Biochemistry, Genetics and Molecular Biology 13 23%
Immunology and Microbiology 8 14%
Medicine and Dentistry 5 9%
Environmental Science 1 2%
Other 2 4%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 July 2011.
All research outputs
#7,719,228
of 12,348,754 outputs
Outputs from Parasite Immunology
#391
of 644 outputs
Outputs of similar age
#54,786
of 85,552 outputs
Outputs of similar age from Parasite Immunology
#5
of 6 outputs
Altmetric has tracked 12,348,754 research outputs across all sources so far. This one is in the 23rd percentile – i.e., 23% of other outputs scored the same or lower than it.
So far Altmetric has tracked 644 research outputs from this source. They receive a mean Attention Score of 2.9. This one is in the 31st percentile – i.e., 31% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 85,552 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one.