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The Immunomodulation and Anti-Inflammatory Effects of Garlic Organosulfur Compounds in Cancer Chemoprevention

Overview of attention for article published in Anti-Cancer Agents in Medicinal Chemistry, February 2014
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#4 of 696)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

news
5 news outlets
twitter
4 tweeters
facebook
2 Facebook pages
googleplus
68 Google+ users
video
4 video uploaders

Citations

dimensions_citation
102 Dimensions

Readers on

mendeley
122 Mendeley
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Title
The Immunomodulation and Anti-Inflammatory Effects of Garlic Organosulfur Compounds in Cancer Chemoprevention
Published in
Anti-Cancer Agents in Medicinal Chemistry, February 2014
DOI 10.2174/18715206113136660370
Pubmed ID
Authors

Georgia Schäfer, Catherine H Kaschula, Catherine H. Kaschula

Abstract

Garlic (Allium sativum) has been used for centuries as a prophylactic and therapeutic medicinal agent. Importantly, garlic has been suggested to have both cancer-preventive potential as well as significant enhancing effects on the immune system. While these observations are supported experimentally both in vitro and in vivo, the impact of garlic in assisting the immune system in the prevention of cancer still lacks experimental confirmation. Studies addressing the immunomodulatory effects of garlic reveal conflicting data as to pro- or anti-inflammatory responses depending on the particular experimental set-ups and the garlic preparation used (i.e. garlic extract versus chemically pure garlic compounds). Here we provide an overview of the chemistry of the major garlic organosulfur compounds, summarize the current understanding and propose a link between the immunomodulating activity of garlic and the prevention of cancer. We hypothesize that garlic rather elicits anti-inflammatory and anti-oxidative responses that aid in priming the organism towards eradication of an emerging tumor.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 122 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
United States 1 <1%
India 1 <1%
Egypt 1 <1%
Unknown 118 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 23 19%
Student > Master 17 14%
Researcher 16 13%
Student > Ph. D. Student 15 12%
Other 12 10%
Other 26 21%
Unknown 13 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 21%
Medicine and Dentistry 18 15%
Biochemistry, Genetics and Molecular Biology 17 14%
Pharmacology, Toxicology and Pharmaceutical Science 10 8%
Nursing and Health Professions 8 7%
Other 25 20%
Unknown 18 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 117. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 May 2020.
All research outputs
#172,546
of 15,635,132 outputs
Outputs from Anti-Cancer Agents in Medicinal Chemistry
#4
of 696 outputs
Outputs of similar age
#2,378
of 262,390 outputs
Outputs of similar age from Anti-Cancer Agents in Medicinal Chemistry
#1
of 22 outputs
Altmetric has tracked 15,635,132 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 696 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 262,390 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.