The Heme Metabolite Carbon Monoxide Facilitates KSHV Infection by Inhibiting TLR4 Signaling in Endothelial Cells

https://t.co/X66Qcori1b "It is not unprecedented for herpesviruses to subvert host proteins to evade TLR4. For example, EBV induces the host microRNA miR-21 (Mrazek et al., 2007), which indirectly attenuates TLR4 signaling via the host protein PDCD4 (Shee

The Heme Metabolite Carbon Monoxide Facilitates KSHV Infection by Inhibiting TLR4 Signaling in Endothelial Cells https://t.co/X66Qcori1b "early HO-1 induction by KSHV results in increased levels of endogenous CO, which functions as a TLR4 signaling inhib