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Vaccine Adjuvants

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Cover of 'Vaccine Adjuvants'

Table of Contents

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    Book Overview
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    Chapter 1 Overview of Vaccine Adjuvants: Introduction, History, and Current Status
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    Chapter 2 Development of the CpG Adjuvant 1018: A Case Study
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    Chapter 3 Syntheses of Human TLR8-Specific Small-Molecule Agonists
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    Chapter 4 Semisynthesis of Analogues of the Saponin Immunoadjuvant QS-21
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    Chapter 5 QS-21 Adjuvant: Laboratory-Scale Purification Method and Formulation Into Liposomes
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    Chapter 6 Purification of an Immunoadjuvant Saponin Fraction from Quillaja brasiliensis Leaves by Reversed-Phase Silica Gel Chromatography
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    Chapter 7 Biosynthetic Approaches to Squalene Production: The Case of Yeast
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    Chapter 8 In Silico Adjuvant Design and Validation
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    Chapter 9 Vaccine Adjuvants
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    Chapter 10 Synthesis of Lymph Node-Targeting Adjuvants
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    Chapter 11 Preparing an Adjuvanted Thermoresponsive Gel Formulation for Sublingual Vaccination
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    Chapter 12 Manufacture of Oil-in-Water Emulsion Adjuvants
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    Chapter 13 Methods to Prepare Aluminum Salt-Adjuvanted Vaccines
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    Chapter 14 Production of Adjuvant-Loaded Biodegradable Particles for Use in Cancer Vaccines
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    Chapter 15 Lyophilization of Adjuvanted Vaccines: Methods for Formulation of a Thermostable Freeze-Dried Product
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    Chapter 16 Stressed Stability Techniques for Adjuvant Formulations
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    Chapter 17 Particle Sizing of Nanoparticle Adjuvant Formulations by Dynamic Light Scattering (DLS) and Nanoparticle Tracking Analysis (NTA)
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    Chapter 18 Quantification of Multiple Components of Complex Aluminum-Based Adjuvant Mixtures by Using Fourier Transform Infrared Spectroscopy and Partial Least Squares Modeling
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    Chapter 19 Determination of Protein Content in Alhydrogel®-Based Vaccines by O-Phthalaldehyde Assay
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    Chapter 20 Staining and Transfer Techniques for SDS-PAGE Gels to Minimize Oil-in-Water Emulsion Adjuvant Interference
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    Chapter 21 Interactions Between Antigens and Nanoemulsion Adjuvants: Separation and Characterization Techniques
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    Chapter 22 Screening Vaccine Formulations in Fresh Human Whole Blood
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    Chapter 23 Analysis of the Innate Response to Adjuvants: Characterization of the Draining Lymph Node by Fluorescence-Activated Cell Sorting
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    Chapter 24 Assessment of Antigen-Specific Cellular Immunogenicity Using Intracellular Cytokine Staining, ELISpot, and Culture Supernatants
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    Chapter 25 Eliciting Epitope-Specific CD8+ T Cell Response by Immunization with Microbial Protein Antigens Formulated with α-Galactosylceramide: Theory, Practice, and Protocols
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    Chapter 26 Molecular Methods and Bioinformatic Tools for Adjuvant Characterization by High-Throughput Sequencing
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