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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Influenza A penetrates host mucus by cleaving sialic acids with neuraminidase
|
|---|---|
| Published in |
Virology Journal, November 2013
|
| DOI | 10.1186/1743-422x-10-321 |
| Pubmed ID | |
| Authors |
Miriam Cohen, Xing-Quan Zhang, Hooman P Senaati, Hui-Wen Chen, Nissi M Varki, Robert T Schooley, Pascal Gagneux |
| Abstract |
Influenza A virus (IAV) neuraminidase (NA) cleaves sialic acids (Sias) from glycans. Inhibiting NA with oseltamivir suppresses both viral infection, and viral release from cultured human airway epithelial cells. The role of NA in viral exit is well established: it releases budding virions by cleaving Sias from glycoconjugates on infected cells and progeny virions. The role of NA in viral entry remains unclear. Host respiratory epithelia secrete a mucus layer rich in heavily sialylated glycoproteins; these could inhibit viral entry by mimicking sialylated receptors on the cell surface. It has been suggested that NA allows influenza to penetrate the mucus by cleaving these sialylated decoys, but the exact mechanism is not yet established. |
X Demographics
The data shown below were collected from the profiles of 33 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 4 | 12% |
| United States | 3 | 9% |
| Spain | 2 | 6% |
| Venezuela, Bolivarian Republic of | 1 | 3% |
| Kenya | 1 | 3% |
| India | 1 | 3% |
| Indonesia | 1 | 3% |
| Colombia | 1 | 3% |
| Netherlands | 1 | 3% |
| Other | 0 | 0% |
| Unknown | 18 | 55% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 22 | 67% |
| Scientists | 5 | 15% |
| Science communicators (journalists, bloggers, editors) | 3 | 9% |
| Practitioners (doctors, other healthcare professionals) | 3 | 9% |
Mendeley readers
The data shown below were compiled from readership statistics for 233 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 1% |
| Japan | 1 | <1% |
| China | 1 | <1% |
| Unknown | 228 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 58 | 25% |
| Student > Bachelor | 38 | 16% |
| Researcher | 27 | 12% |
| Student > Master | 21 | 9% |
| Student > Doctoral Student | 11 | 5% |
| Other | 30 | 13% |
| Unknown | 48 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 47 | 20% |
| Biochemistry, Genetics and Molecular Biology | 43 | 18% |
| Immunology and Microbiology | 28 | 12% |
| Chemistry | 15 | 6% |
| Medicine and Dentistry | 13 | 6% |
| Other | 33 | 14% |
| Unknown | 54 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 134. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 May 2023.
All research outputs
#298,075
of 24,713,766 outputs
Outputs from Virology Journal
#25
of 3,292 outputs
Outputs of similar age
#2,643
of 313,793 outputs
Outputs of similar age from Virology Journal
#2
of 63 outputs
Altmetric has tracked 24,713,766 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,292 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.9. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,793 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 63 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.