Zinaida M Kaskova, Felipe A Dörr, Valentin N Petushkov, Konstantin V Purtov, Aleksandra S Tsarkova, Natalja S Rodionova, Konstantin S Mineev, Elena B Guglya, Alexey Kotlobay, Nadezhda S Baleeva, Mikhail S Baranov, Alexander S Arseniev, Josef I Gitelson, Sergey Lukyanov, Yoshiki Suzuki, Shusei Kanie, Ernani Pinto, Paolo Di Mascio, Hans E Waldenmaier, Tatiana A Pereira, Rodrigo P Carvalho, Anderson G Oliveira, Yuichi Oba, Erick L Bastos, Cassius V Stevani, Ilia V Yampolsky
Abstract
Bioluminescent fungi are spread throughout the globe, but details on their mechanism of light emission are still scarce. Usually, the process involves three key components: an oxidizable luciferin substrate, a luciferase enzyme, and a light emitter, typically oxidized luciferin, and called oxyluciferin. We report the structure of fungal oxyluciferin, investigate the mechanism of fungal bioluminescence, and describe the use of simple synthetic α-pyrones as luciferins to produce multicolor enzymatic chemiluminescence. A high-energy endoperoxide is proposed as an intermediate of the oxidation of the native luciferin to the oxyluciferin, which is a pyruvic acid adduct of caffeic acid. Luciferase promiscuity allows the use of simple α-pyrones as chemiluminescent substrates.
This research output has an Altmetric Attention Score of 401. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 December 2023.
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#80,868
of 26,742,223 outputs
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#883
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#1,809
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Outputs of similar age from Science Advances
#13
of 201 outputs
Altmetric has tracked 26,742,223 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,539 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 117.6. This one has done particularly well, scoring higher than 93% of its peers.
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We're also able to compare this research output to 201 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.
