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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model
|
|---|---|
| Published in |
Nature Genetics, December 2013
|
| DOI | 10.1038/ng.2847 |
| Pubmed ID | |
| Authors |
Emilie A Bard-Chapeau, Anh-Tuan Nguyen, Alistair G Rust, Ahmed Sayadi, Philip Lee, Belinda Q Chua, Lee-Sun New, Johann de Jong, Jerrold M Ward, Christopher K Y Chin, Valerie Chew, Han Chong Toh, Jean-Pierre Abastado, Touati Benoukraf, Richie Soong, Frederic A Bard, Adam J Dupuy, Randy L Johnson, George K Radda, Eric Chun Yong Chan, Lodewyk F A Wessels, David J Adams, Nancy A Jenkins, Neal G Copeland |
| Abstract |
The most common risk factor for developing hepatocellular carcinoma (HCC) is chronic infection with hepatitis B virus (HBV). To better understand the evolutionary forces driving HCC, we performed a near-saturating transposon mutagenesis screen in a mouse HBV model of HCC. This screen identified 21 candidate early stage drivers and a very large number (2,860) of candidate later stage drivers that were enriched for genes that are mutated, deregulated or functioning in signaling pathways important for human HCC, with a striking 1,199 genes being linked to cellular metabolic processes. Our study provides a comprehensive overview of the genetic landscape of HCC. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 164 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 1% |
| Netherlands | 1 | <1% |
| Hong Kong | 1 | <1% |
| Chile | 1 | <1% |
| Japan | 1 | <1% |
| United Kingdom | 1 | <1% |
| Unknown | 157 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 38 | 23% |
| Researcher | 37 | 23% |
| Student > Master | 17 | 10% |
| Student > Bachelor | 12 | 7% |
| Student > Doctoral Student | 10 | 6% |
| Other | 29 | 18% |
| Unknown | 21 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 49 | 30% |
| Biochemistry, Genetics and Molecular Biology | 37 | 23% |
| Medicine and Dentistry | 30 | 18% |
| Computer Science | 5 | 3% |
| Psychology | 3 | 2% |
| Other | 14 | 9% |
| Unknown | 26 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 May 2018.
All research outputs
#1,503,573
of 22,736,112 outputs
Outputs from Nature Genetics
#2,206
of 7,182 outputs
Outputs of similar age
#18,251
of 306,779 outputs
Outputs of similar age from Nature Genetics
#28
of 65 outputs
Altmetric has tracked 22,736,112 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,182 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 41.0. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 306,779 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 65 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.