↓ Skip to main content

The combination of L-4F and simvastatin stimulate cholesterol efflux and related proteins expressions to reduce atherosclerotic lesions in apoE knockout mice

Overview of attention for article published in Lipids in Health and Disease, December 2013
Altmetric Badge

Citations

dimensions_citation
16 Dimensions

Readers on

mendeley
19 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
The combination of L-4F and simvastatin stimulate cholesterol efflux and related proteins expressions to reduce atherosclerotic lesions in apoE knockout mice
Published in
Lipids in Health and Disease, December 2013
DOI 10.1186/1476-511x-12-180
Pubmed ID
Authors

Ru Ying, Yong Yuan, Ya-Fei Qin, Di Tian, Li Feng, Zhi-Gang Guo, Yan-Xiang Sun, Ming-Xing Li

Abstract

Both L-4F, one apolipoprotein A-1 mimetic peptide, and statins can reduce progression of atherosclerosis by different mechanisms. The combination of the two drugs can cause lesion regression by rendering HDL anti-inflammatory. We postulated that combination of L-4F and simvastatin may stimulate cholesterol efflux and related proteins expressions to alleviate atherosclerosis.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 2 11%
United States 1 5%
Canada 1 5%
Unknown 15 79%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 26%
Student > Ph. D. Student 4 21%
Student > Postgraduate 3 16%
Lecturer 1 5%
Other 1 5%
Other 2 11%
Unknown 3 16%
Readers by discipline Count As %
Medicine and Dentistry 8 42%
Agricultural and Biological Sciences 4 21%
Pharmacology, Toxicology and Pharmaceutical Science 2 11%
Chemistry 1 5%
Unknown 4 21%