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Berberine chloride can ameliorate the spatial memory impairment and increase the expression of interleukin-1beta and inducible nitric oxide synthase in the rat model of Alzheimer's disease

Overview of attention for article published in BMC Neuroscience, December 2006
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  • Good Attention Score compared to outputs of the same age (74th percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Mentioned by

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1 X user
patent
1 patent
facebook
1 Facebook page

Citations

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166 Dimensions

Readers on

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97 Mendeley
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Title
Berberine chloride can ameliorate the spatial memory impairment and increase the expression of interleukin-1beta and inducible nitric oxide synthase in the rat model of Alzheimer's disease
Published in
BMC Neuroscience, December 2006
DOI 10.1186/1471-2202-7-78
Pubmed ID
Authors

Feiqi Zhu, Caiyun Qian

Abstract

Berberine is the major alkaloidal component of Rhizoma coptidis, and has multiple pharmacological effects including inhibiting acetylcholinesterase, reducing cholesterol and glucose, lowering mortality in patients with chronic congestive heart failure and anti-inflammation etc. Thus berberine is a promising drug for diabetes, hyperlipemia, coronary artery disease and ischemic stroke etc. The present study was carried out to investigate the effect of berberine chloride on the spatial memory, inflammation factors interleukin-1 beta (IL-1beta) and inducible nitric oxide synthase (iNOS) expression in the rat model of Alzheimer's disease (AD) which was established by injecting Abeta (1-40) (5 microgram) into the rats hippocampuses bilaterally.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 97 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Iran, Islamic Republic of 1 1%
Malaysia 1 1%
Poland 1 1%
Unknown 94 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 13%
Student > Master 12 12%
Student > Bachelor 11 11%
Researcher 9 9%
Professor > Associate Professor 9 9%
Other 19 20%
Unknown 24 25%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 14%
Medicine and Dentistry 14 14%
Pharmacology, Toxicology and Pharmaceutical Science 12 12%
Chemistry 6 6%
Biochemistry, Genetics and Molecular Biology 5 5%
Other 12 12%
Unknown 34 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 July 2021.
All research outputs
#6,772,066
of 22,736,112 outputs
Outputs from BMC Neuroscience
#326
of 1,241 outputs
Outputs of similar age
#39,167
of 155,570 outputs
Outputs of similar age from BMC Neuroscience
#1
of 7 outputs
Altmetric has tracked 22,736,112 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 1,241 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 155,570 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them