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The development of bispecific antibodies and their applications in tumor immune escape

Overview of attention for article published in Experimental Hematology & Oncology, May 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#19 of 133)
  • Good Attention Score compared to outputs of the same age (73rd percentile)

Mentioned by

twitter
7 tweeters
patent
1 patent

Citations

dimensions_citation
41 Dimensions

Readers on

mendeley
84 Mendeley
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Title
The development of bispecific antibodies and their applications in tumor immune escape
Published in
Experimental Hematology & Oncology, May 2017
DOI 10.1186/s40164-017-0072-7
Pubmed ID
Authors

Xiaolong Zhang, Yuanyuan Yang, Dongmei Fan, Dongsheng Xiong

Abstract

During the past two decades, a great evolution of bispecific antibodies (BsAbs) for therapeutic applications has been made. BsAbs can bind simultaneously two different antigens or epitopes, which leads to a wide range of applications including redirecting T cells or NK cells to tumor cells, blocking two different signaling pathways, dual targeting of different disease mediators, and delivering payloads to targeted sites. Aside from approved catumaxomab (anti-CD3 and anti-EpCAM) and blinatumomab (anti-CD3 and anti-CD19), many more BsAbs are now in various phases of clinical development. Here, this review focus on the development of bispecific antibodies and their applications in tumor immune escape.

Twitter Demographics

The data shown below were collected from the profiles of 7 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Russia 1 1%
France 1 1%
Unknown 82 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 24%
Student > Ph. D. Student 14 17%
Other 13 15%
Student > Bachelor 11 13%
Student > Doctoral Student 6 7%
Other 13 15%
Unknown 7 8%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 20 24%
Agricultural and Biological Sciences 18 21%
Medicine and Dentistry 12 14%
Immunology and Microbiology 12 14%
Pharmacology, Toxicology and Pharmaceutical Science 6 7%
Other 8 10%
Unknown 8 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 December 2018.
All research outputs
#2,832,956
of 14,805,703 outputs
Outputs from Experimental Hematology & Oncology
#19
of 133 outputs
Outputs of similar age
#68,838
of 264,396 outputs
Outputs of similar age from Experimental Hematology & Oncology
#1
of 2 outputs
Altmetric has tracked 14,805,703 research outputs across all sources so far. Compared to these this one has done well and is in the 77th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 133 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,396 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them