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Antifungal activity of synthetic antiseptics and natural compounds against Candida dubliniensis before and after in vitro fluconazole exposure

Overview of attention for article published in Revista da Sociedade Brasileira de Medicina Tropical, February 2017
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About this Attention Score

  • Among the highest-scoring outputs from this source (#50 of 216)
  • Average Attention Score compared to outputs of the same age
  • Above-average Attention Score compared to outputs of the same age and source (61st percentile)

Mentioned by

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3 tweeters

Citations

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5 Dimensions

Readers on

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28 Mendeley
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Title
Antifungal activity of synthetic antiseptics and natural compounds against Candida dubliniensis before and after in vitro fluconazole exposure
Published in
Revista da Sociedade Brasileira de Medicina Tropical, February 2017
DOI 10.1590/0037-8682-0461-2016
Pubmed ID
Authors

Cássia Franco Reginato, Laíssa Arévalo Bandeira, Régis Adriel Zanette, Janio Morais Santurio, Sydney Hartz Alves, Cristiane Cademartori Danesi

Abstract

This study evaluated the susceptibilities of oral candidiasis-derived Candida albicans, fluconazole-resistant (FR) Candida dubliniensis, and fluconazole-susceptible (FS) C. dubliniensis to synthetic antiseptics [chlorhexidine gluconate (CHX), cetylpyridinium chloride (CPC), and triclosan (TRC)] and natural compounds (carvacrol, eugenol and thymol). Susceptibility tests were performed based on the M27-A3 reference method. The fluconazole-resistant C. dubliniensis strains were obtained after prolonged in vitro exposure to increasing fluconazole concentrations. The geometric mean values for minimum inhibitory concentrations and minimum fungicidal concentrations were compared among the groups. Fluconazole-susceptible C. dubliniensis was more sensitive to CPC and TRC than FR C. dubliniensis and C. albicans were. However, eugenol and thymol were more active against FR C. dubliniensis. The fungicidal activities of CHX and TRC were similar for the three groups, and FR C. dubliniensis and C. albicans had similar sensitivities to CPC. The resistance of C. dubliniensis to fluconazole affects its sensitivity the synthetic antiseptics and natural compounds that were tested.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 25%
Student > Ph. D. Student 5 18%
Professor 5 18%
Student > Master 4 14%
Student > Doctoral Student 2 7%
Other 1 4%
Unknown 4 14%
Readers by discipline Count As %
Medicine and Dentistry 8 29%
Pharmacology, Toxicology and Pharmaceutical Science 5 18%
Chemistry 4 14%
Environmental Science 2 7%
Biochemistry, Genetics and Molecular Biology 1 4%
Other 3 11%
Unknown 5 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 May 2017.
All research outputs
#7,860,188
of 12,527,863 outputs
Outputs from Revista da Sociedade Brasileira de Medicina Tropical
#50
of 216 outputs
Outputs of similar age
#147,123
of 259,306 outputs
Outputs of similar age from Revista da Sociedade Brasileira de Medicina Tropical
#5
of 13 outputs
Altmetric has tracked 12,527,863 research outputs across all sources so far. This one is in the 23rd percentile – i.e., 23% of other outputs scored the same or lower than it.
So far Altmetric has tracked 216 research outputs from this source. They receive a mean Attention Score of 1.4. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 259,306 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.