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RAD51Cdeletion screening identifies a recurrent gross deletion in breast cancer and ovarian cancer families

Overview of attention for article published in Breast Cancer Research, December 2013
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1 Facebook page

Citations

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29 Dimensions

Readers on

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24 Mendeley
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1 CiteULike
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Title
RAD51Cdeletion screening identifies a recurrent gross deletion in breast cancer and ovarian cancer families
Published in
Breast Cancer Research, December 2013
DOI 10.1186/bcr3589
Pubmed ID
Authors

Gioia Schnurbein, Jan Hauke, Barbara Wappenschmidt, Nana Weber-Lassalle, Stefanie Engert, Heide Hellebrand, Lutz Garbes, Alexandra Becker, Guido Neidhardt, Kerstin Rhiem, Alfons Meindl, Rita K Schmutzler, Eric Hahnen

Abstract

RAD51C is an integral part of the DNA double-strand repair through homologous recombination, and monoallelic mutations were found in ~1.3% of BRCA1/2-negative breast cancer (BC) and/or ovarian cancer (OC) families. Several studies confirmed the occurrence of RAD51C mutations predominantly in BC and/or OC families, although with varying frequencies, clearly establishing RAD51C as a cancer-predisposing gene. There is ongoing debate whether pathogenic RAD51C alterations increase the relative risk for BC in addition to that for OC, which was estimated to be 5.88 (95% confidence interval = 2.91 to 11.88; P = 7.65 × 10-7).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 4%
Unknown 23 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 33%
Researcher 6 25%
Student > Master 3 13%
Student > Doctoral Student 2 8%
Other 1 4%
Other 2 8%
Unknown 2 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 50%
Biochemistry, Genetics and Molecular Biology 4 17%
Medicine and Dentistry 3 13%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Chemistry 1 4%
Other 1 4%
Unknown 2 8%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 December 2013.
All research outputs
#22,759,802
of 25,374,917 outputs
Outputs from Breast Cancer Research
#1,883
of 2,053 outputs
Outputs of similar age
#281,867
of 320,461 outputs
Outputs of similar age from Breast Cancer Research
#25
of 34 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,053 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,461 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.