Nature子刊 | 西妥昔单抗耐药又一元凶浮出水面
CN-Healthcare,
引言 大部分结直肠癌(CRC)的发生和发展都依赖于EGFR/KRAS/BRAF/MAPK信号通路的异常活化。 而今,Anti-EGFR(西妥昔单抗)或者Anti-VEGF(贝伐珠单抗)与化疗联用都有效提高了CRC患者的治疗效果[1]。但KRAS的初始突变会导…
引言 大部分结直肠癌(CRC)的发生和发展都依赖于EGFR/KRAS/BRAF/MAPK信号通路的异常活化。 而今,Anti-EGFR(西妥昔单抗)或者Anti-VEGF(贝伐珠单抗)与化疗联用都有效提高了CRC患者的治疗效果[1]。但KRAS的初始突变会导…
Abstract DNA can determine where and when genes are expressed, but the full set of sequence determinants that control gene…
Researchers at Memorial Sloan Kettering Cancer Center in New York have discovered that cancer cells with high numbers of faults…
Consider this a letter to the internet. It relates to my column on why CMS and other payers should cover the costs of genomic…