| Chapter title |
IL-9: Function, Sources, and Detection
|
|---|---|
| Chapter number | 2 |
| Book title |
Th9 Cells
|
| Published in |
Methods in molecular biology, January 2017
|
| DOI | 10.1007/978-1-4939-6877-0_2 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-6876-3, 978-1-4939-6877-0
|
| Authors |
Wilmer Gerardo Rojas-Zuleta M.D., Elizabeth Sanchez M.D., Wilmer Gerardo Rojas-Zuleta, Elizabeth Sanchez, Rojas-Zuleta, Wilmer Gerardo, Sanchez, Elizabeth |
| Editors |
Ritobrata Goswami |
| Abstract |
IL-9 is a pleiotropic cytokine produced in different amounts by a wide variety of cells including mast cells, NKT cells, Th2, Th17, Treg, ILC2, and Th9 cells. Th9 cells are considered to be the main CD4+ T cells that produce IL-9. IL-9 exerts its effects on multiple types of cells and different tissues. To date, its main role has been found in the immune responses against parasites and pathogenesis of allergic diseases such as asthma and bronchial hyperreactivity. Additionally, it induces the proliferation of hematologic neoplasias, including Hodgkin's lymphoma in humans. However, IL-9 also has antitumor properties in solid tumors such as melanoma. The objective of this review is to describe IL-9, its function, sources, and methods of detection. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 48 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 11 | 23% |
| Student > Bachelor | 7 | 15% |
| Researcher | 4 | 8% |
| Student > Doctoral Student | 2 | 4% |
| Student > Ph. D. Student | 2 | 4% |
| Other | 5 | 10% |
| Unknown | 17 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 7 | 15% |
| Biochemistry, Genetics and Molecular Biology | 6 | 13% |
| Immunology and Microbiology | 6 | 13% |
| Agricultural and Biological Sciences | 4 | 8% |
| Engineering | 2 | 4% |
| Other | 1 | 2% |
| Unknown | 22 | 46% |