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microRNAs: important regulators of stem cells

Overview of attention for article published in Stem Cell Research & Therapy, May 2017
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Title
microRNAs: important regulators of stem cells
Published in
Stem Cell Research & Therapy, May 2017
DOI 10.1186/s13287-017-0551-0
Pubmed ID
Authors

Na Li, Bo Long, Wei Han, Shumin Yuan, Kun Wang

Abstract

Stem cells are undifferentiated cells and have multi-lineage differentiation potential. Generally, stem cells are classified into adult stem cells, embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). Stem cells have great potential in clinical therapy due to their pluripotency and self-renewal ability. microRNAs (miRNAs) are small non-coding RNAs which are evolutionarily conserved and participate in the pathogenesis of many diseases, cell cycle regulation, apoptosis, aging, cell fate decisions, and different signaling pathways. Different kinds of stem cells possess distinct miRNA expression profiles. Our review summarizes the critical roles of miRNAs in stem cell reprogramming, pluripotency maintenance, and differentiation. In the future, miRNAs may greatly contribute to stem cell clinical therapy and have potential applications in regenerative medicine.

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X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 150 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 <1%
Unknown 149 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 13%
Student > Bachelor 17 11%
Student > Master 16 11%
Researcher 11 7%
Student > Doctoral Student 10 7%
Other 28 19%
Unknown 48 32%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 44 29%
Agricultural and Biological Sciences 18 12%
Medicine and Dentistry 12 8%
Pharmacology, Toxicology and Pharmaceutical Science 5 3%
Neuroscience 5 3%
Other 15 10%
Unknown 51 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 April 2018.
All research outputs
#15,459,013
of 22,971,207 outputs
Outputs from Stem Cell Research & Therapy
#1,349
of 2,428 outputs
Outputs of similar age
#195,260
of 310,860 outputs
Outputs of similar age from Stem Cell Research & Therapy
#41
of 60 outputs
Altmetric has tracked 22,971,207 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,428 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 310,860 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 60 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.